Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation

Liver Transplant; Complications Clinical Trial

Official title:

Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation in Al-Rajhy Liver Hospital in Upper Egypt.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03789383
• Other study ID #: RFLTIUNE
• Status: Not yet recruiting
• Start date: January 1, 2020
• Est. completion date: February 1, 2022

Study information

• Verified date: July 2019
• Source: Assiut University
• Contact: Sara Sedeek
• Phone: +201022177340
• Email: sara_ali[@]aun.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Liver transplantation (LT) is a live-saving therapy for patients with complicated chronic liver diseases and acute liver failure .Even though many complications can occur after LT, biliary complications (BC) are both common and potentially severe .

a prospective study and retrospective part from hospital records.

Aim of the study:

1. Detect frequency, risk factors for development of biliary complications post living donor liver transplantation, types (stricture anastomotic or not, leak, biloma, stone, cholangitis etc.…).

2. Evaluate outcomes of different biliary complications

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: February 1, 2022
• Est. primary completion date: December 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Adults more than 18 y with living donor liver transplantation in Al-Rajhy liver hospital , Assiut university,Egypt

Exclusion Criteria:

• pediatric liver transplantation

• cadaveric liver transplantation

Related Conditions & MeSH terms

• Liver Transplant; Complications

Locations

Country	Name	City	State
Egypt	Al-Rajhy liver hospital	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of biliary complications	Biliary complications include biliary leak or stricture (anastomotic or non anastomotic), the investigator will record nature of complication , its time of presentation and number of hospital re-admissions due to biliary complications.	1 year after liver transplantation
Primary	Type of intervention done to each complication	Intervention is either non surgical (ERCP or PTD) or surgical revision with detailed description of each intervention and if the intervention is successful or not (biliary stricture resolved by MRCP, improvement of liver functions and symptoms)	1 year after liver transplantation