Remote Ischemic Preconditioning in Liver Transplantation

Liver Transplanatation Clinical Trial

— RIRI  

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02534025
• Other study ID #: 1/2015
• Status: Recruiting
• Phase: N/A
• First received: August 9, 2015
• Last updated: February 5, 2017
• Start date: January 2016
• Est. completion date: March 2017

Study information

• Verified date: February 2017
• Source: Mansoura University
• Contact: AlRefaey Kandeel, MD
• Phone: +201008158591
• Email: refa3ey2[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Remote (upper arm) ischemic preconditioning in the donor of living donor liver transplanta to ameliorate the effect of reperfusion injury in recipients.

Description:

Upper arm ischemia will be induced by elevation of NIBP cuff pressure to 200 mm Hg for 5 minutes repeated four times 5 mniutes apart, aiming to decrease the effect of ischemia reperfusion in the graft liver.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: March 2017
• Est. primary completion date: February 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 30 Years to 60 Years

Eligibility

Inclusion Criteria:

• All candidates for living donor liver transplantation

Exclusion Criteria:

• Donors with peripheral vascular disease

Related Conditions & MeSH terms

• Liver Transplanatation

Intervention

Procedure:
• Ischemia preconditioining
Elavate blood pressure cuff pressure to 200

Locations

Country	Name	City	State
Egypt	Mansoura university	Mansoura	Dkahleya

Sponsors (1)

Lead Sponsor	Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	liver enzymes ( SGOT and SGPT) as indicator of graft injury	Hemodynamic effects of reperfusion ijury	30 minutes