Cardiac Functions in Living Donor Liver Transplant Recipients. An Echocardiographic Study.

Liver Transplant Clinical Trial

Official title:

Cardiac Functions in Living Donor Liver Transplant Recipients. An Echocardiographic Study.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01840514
• Other study ID #: 1982
• Status: Recruiting
• Phase: N/A
• First received: April 23, 2013
• Last updated: October 4, 2013
• Start date: December 2012
• Est. completion date: September 2015

Study information

• Verified date: October 2013
• Source: Mansoura University
• Contact: amr M yassen, MD
• Phone: +201001497044
• Email: amryassen[@]hotmail.com
• Is FDA regulated: No
• Health authority: Egypt: mansoura faculty of medicine
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The stress of orthotopic living donor liver transplantation in patients with cirrhosis could induce worsening of an already recorded myocardial dysfunction or may be associated with a new myocardial dysfunction in patients previously having normal myocardial functions, therefore this study will be designed for intra-operative detection of new onset ventricular dysfunction or worsening of already diagnosed ventricular dysfunction in living donor liver transplant recipient and the possible contribution of several hemodynamic and oxygenation parameters in the generation of any cardiovascular function impairment will be also investigated and to determine the impact of ventricular dysfunction on early (7 PO days) graft function, 28 days survival and patient outcomes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: September 2015
• Est. primary completion date: April 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• all adult recipient

Exclusion Criteria:

• massive blood transfusion

• grade III esophageal varices

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Liver Transplant

Locations

Country	Name	City	State
Egypt	Liver transplantation program - Gastroenterology surgical center	Mansoura	Dakahlia
Egypt	Liver transplantation project - Gastroenterology surgical center - Mansoura university	Mansoura	Dakahlia

Sponsors (1)

Lead Sponsor	Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	survival		28 days	Yes
Primary	hemodynamic monitoring		intraoperative	Yes
Secondary	graft function		7 days	Yes