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Correlation of Ultrasound Based Measurements of Liver Stiffness and Steatosis With MRI

Liver Cirrhosis Clinical Trial

Official title:
Correlation of Ultrasound Based Measurements of Liver Stiffness and Steatosis With MRI

Clinical Trial Summary

The investigators will assess the ability of ultrasound (US) to measure liver stiffness (cirrhosis) and liver fat content (steatosis).

Clinical Trial Description

Non-invasive monitoring of liver fibrosis using magnetic resonance imaging (MRI) can help determine which patients will most benefit from interventional therapies to help reverse the condition. Similarly, quantitative assessment of liver fat content using MRI can assist physicians in identifying patients at risk for hepatic steatohepatitis. Due to the widespread dissemination of US machines and their relative lower cost compared to other imaging modalities, e.g. MRI, the ability of US to assess these parameters widens diagnostic availability. Patients who have undergone an MRI exam to assess liver stiffness (cirrhosis) and/or liver fat content (steatosis) will be asked to undergo an US exam to assess the same parameters. The cirrhosis and steatosis measurements obtained from both exams will be compared. If US-based measurements of liver stiffness and/or liver fat content are shown to be reproducible and accurate when compared to MRI values (will be used as the gold standard), US may become the first-line diagnostic test for these liver conditions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03342703
Study type Observational
Source Stanford University
Contact
Status Completed
Phase
Start date August 1, 2018
Completion date December 31, 2020
View Details
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