Liver Injury Clinical Trial
— ASEPOLOfficial title:
Automatic Segmentation by a Convolutional Neural Network (Artificial Intelligence - Deep Learning) of Polycystic Livers, as a Model of Multi-lesional Dysmorphic Livers
NCT number | NCT03960710 |
Other study ID # | ASEPOL |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | April 1, 2019 |
Est. completion date | September 2019 |
Assessing the volume of the liver before surgery, predicting the volume of liver remaining
after surgery, detecting primary or secondary lesions in the liver parenchyma are common
applications that require optimal detection of liver contours, and therefore liver
segmentation.
Several manual and laborious, semi-automatic and even automatic techniques exist.
However, severe pathology deforming the contours of the liver (multi-metastatic livers...),
the hepatic environment of similar density to the liver or lesions, the CT examination
technique are all variables that make it difficult to detect the contours. Current
techniques, even automatic ones, are limited in this type of case (not rare) and most often
require readjustments that make automatisation lose its value.
All these criteria of segmentation difficulties are gathered in the livers of hepatorenal
polycystosis, which therefore constitute an adapted study model for the development of an
automatic segmentation tool.
To obtain an automatic segmentation of any lesional liver, by exceeding the criteria of
difficulty considered, investigators have developed a convolutional neural network
(artificial intelligence - deep learning) useful for clinical practice.
Status | Recruiting |
Enrollment | 120 |
Est. completion date | September 2019 |
Est. primary completion date | July 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Patients = 18 years old - Patients with hepato-renal polycystosis, with or without surgery - Patients with at least one abdominal-pelvic CT scan without injection or with injection between January 1, 2016 and August 2018 - Patients with good quality and available images Exclusion Criteria: - Patients with no CT scan images available - Patients with bad quality of CT scan images |
Country | Name | City | State |
---|---|---|---|
France | Service de radiologie - Pavillon B - Cellule Recherche imagerie, Hôpital Edouard Herriot (HCL) | Lyon |
Lead Sponsor | Collaborator |
---|---|
Hospices Civils de Lyon |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Test of automatic segmentation by the convolutional neural network on these group and collection of data set | Development of an automatic segmentation tool for highly dysmorphic polycystic livers as a prerequisite for segmentation of any type of multi-lesional livers that are difficult to segment, in order to facilitate lesion detection and volume measurement in clinical practice. Randomisation of the patient into two data groups, one for training the other for Validating the convolutional neural network (artificial intelligence) Manual segmentation of polycystic livers of the 1st training group and deep learning of convolutional neural network Manual segmentation of polycystic livers of 2nd validation group Test of automatic segmentation by the convolutional neural network on these group and collection of data set |
At 4 months after randomization |
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