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Clinical Trial Summary

The investigated cohort will examine liver and spleen fibrosis in patients with Gaucher Disease(GD) by using Shear Wave Elastography- SWE to evaluation fibrosis of the tissue and to check the correlation of fibrosis with the biomarkers of disease severity.


Clinical Trial Description

To assess liver and spleen stiffness measurement using Shear Wave Elastography-SWE and evaluate liver and spleen fibrosis in patients with Gaucher Disease. To compare the elastography with the biomarkers that taken at the GD haematology clinic and to check the correlation with severity of liver and spleen fibrosis. SWE is a safe with diagnostic accuracy regarding the liver (& Spleen) fibrosis. Estimating spleen fibrosis is an innovative approach in liver disease and Gaucher. The evaluation of fibrosis with this relatively new and safe method could avoid complications and invasive procedure in GD patients . ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03896607
Study type Observational
Source HaEmek Medical Center, Israel
Contact
Status Terminated
Phase
Start date March 30, 2019
Completion date October 31, 2022

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