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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03371537
Other study ID # RIPH3-RNI17/DEBIFOIE
Secondary ID 2017-A01754-4920
Status Completed
Phase
First received
Last updated
Start date October 8, 2017
Est. completion date March 19, 2019

Study information

Verified date March 2021
Source University Hospital, Tours
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Hepatocellular insufficiency is a dreaded complication after hepatectomy, since, if it is persistent, it leads to the death of the patient in the absence of liver transplantation. The preoperative evaluation aims in particular to estimate the risk of postoperative hepatocellular insufficiency so as to minimize or contraindicate high-risk patients. It has been shown that the flow of the portal vein is correlated with liver function, especially in the living donor and after portal embolization. More recently, the study of flow rates in the portal vein and the hepatic artery after transplantation has shown a correlation with the recovery of graft function. The hypothesis is that portal and arterial flow after hepatectomy can predict postoperative hepatocellular function.


Description:

Measurements of flow rates in the portal vein and the hepatic artery by different transit times are available thanks to the Medistim VeriQTM system that the investigators already use routinely in the context of liver transplantation when performing hepatectomies.


Recruitment information / eligibility

Status Completed
Enrollment 9
Est. completion date March 19, 2019
Est. primary completion date March 19, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - patient 18 years or more - Patient undergoing laparotomy for liver resection Exclusion Criteria: - Patient under tutorship or curatorship - Pregnant or lactating woman - Difficulties in understanding French - Patient operated by laparoscopy - Patient having objected to the processing of his data

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Liver debit measure
Mesure of liver debit during hepatectomy

Locations

Country Name City State
France Service de Chirurgie Digestive, Oncologique, Endocrinienne et Transplantation Hépatique, CHRU de TOURS Tours

Sponsors (1)

Lead Sponsor Collaborator
University Hospital, Tours

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Liver vessel debit Mesure of liver debit during hepatectomy Baseline
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