Liver Dysfunction Clinical Trial
Official title:
To Observe Mivacurium Chloramine Muscle Relaxation Effect in the Operation Anesthesia Patients With Liver Cirrhosis
Observed the muscle relaxation of mivacurium in patients with liver cirrhosis.Clear of mivacurium in patients with liver cirrhosis without muscle relaxant accumulation and delayed recovery phenomenon
The liver is an important organ of the body to maintain life activities, material and energy
metabolism, and the main organ of biotransformation and elimination of toxic substances and
drugs, have many complex functions. Anesthetic drugs mostly through liver transformation and
degradation.Liver cirrhosis, liver cancer patients due to abnormal liver dysfunction and
liver metabolism, Most of the muscle relaxant prone to muscle relaxant accumulation and
delayed recovery of patients with liver cirrhosis.
Mivacurium is a new type of non depolarizing muscle relaxants，has the characteristics of
rapid onset, short duration of action. Mivacurium can produce similar clinical effect of
depolarizing muscle relaxant succinylcholine, and rapidly be blood Che catabolism, Without
liver metabolism. It can either as a single vein for medicinal endotracheal intubation, or
as maintain continuous intravenous auxiliary anesthesia drug , is a muscle relaxant to
shorten the clinical anesthesia recovery period ideal.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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