High Resolution HBA-MRI Using Deep Learning Reconstruction

Liver Diseases Clinical Trial

Official title:

AIRTM Deep Learning Reconstruction of Abdominal High Resolution Gd-EOB-DTPA Enhanced MRI in Patients With Suspicious Focal Liver Lesions: Image Quality Assessment

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05182099
• Other study ID #: 2021-3044
• Status: Active, not recruiting
• Phase: N/A
• Start date: January 10, 2022
• Est. completion date: September 30, 2023

Study information

• Verified date: May 2023
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study aims to compare image qualities between conventionally reconstructed MRI sequences and deep-learning reconstructed MRI sequences from the same data in patients who undergo Gd-EOB-DTPA enhanced liver MRI. The AIRTM deep learning sequence is applicable for various MRI sequences including T2-weighted image (T2WI), T1-weighted image and diffusion-weighted image (DWI). We plan to perform intra-individual comparisons of the image qualities between two reconstructed image datasets.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 52
• Est. completion date: September 30, 2023
• Est. primary completion date: March 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• older than 20 years old

• scheduled for Gd-EOB-DTPA enhanced liver MRI at a 3T scanner (Premier, GE Healthcare) in our institution

• signed informed consent

Exclusion Criteria:

• younger than 20 years old

• any absolute/relative contrast indication of Gd-EOB-DTPA enhanced MRI

• history of transient dyspnea after Gd-EOB-DTPA administration

Related Conditions & MeSH terms

• Deep Learning
• Liver Diseases
• Magnetic Resonance Imaging

Intervention

Diagnostic Test:
• Liver MRI
Gd-EOB-DTPA enhanced MRI consists of T2-weighted image (T2WI), diffusion weighted image (DWI) and precontrast T1-weighted image (T1WI), dynamic T1WI (arterial, portal and transitional phases), and hepatobiliary phase.

Locations

Country	Name	City	State
Korea, Republic of	Seoul National University Hospital	Seoul

Sponsors (2)

Lead Sponsor	Collaborator
Seoul National University Hospital	GE Healthcare

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overall image quality of arterial phase	qualitative assessment of arterial phase on a five point scale (highest score indicates better image quality)	3 months after enrollment completion