Liver Disease Clinical Trial
Official title:
Biochemical and Echosonographic Impacts Using Siliphos-Selenium-Methionine-Alpha Lipoic Acid + Metformin Versus Metformin in Patients With Fatty Liver and Steatohepatitis
Non-alcoholic steatohepatitis represents 10 - 15% total cases of hepatic cirrhosis. In the
upcoming years, the economic burden of this disease will increase and will mean an important
problem for our health system due to obesity epidemic.
There are several treatments for non-alcoholic steatohepatitis; however, none of them have
overcome a healthy lifestyle including diet, exercise and some drugs related with insulin
metabolism.
There after, using hepatoprotective drugs and antioxidants have been recommended as an
eligible therapy to reduce the progression from fatty liver to steatohepatitis and
cirrhosis. Being this approach not only an experimental item yet but also an unavoidable
reality.
The purpose of this randomized controlled study is explore the effects of
siliphos-selenium-methionine-alpha lipoic acid + metformin versus metformin in patients with
fatty liver and non-alcoholic steatohepatitis about biochemical and echosonographic
parameters.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care
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