Clinical Trials Logo

Clinical Trial Summary

This is a prospective, observational study to establish a repository of samples from patients with extreme lipid phenotypes including but not limited to hyperlipidemia, dyslipidemia, hyperlipoproteinemia, extreme low/high HDL levels and deranged lipoprotein metabolism. The investigators plan to conduct sophisticated composition and functional analyses as well as genetic analysis to better understand the determinants of extreme lipid derangements.


Clinical Trial Description

Participants will be recruited from clinical encounters within the University of Texas (UT) Southwestern Medical Center and Parkland Hospital by screening the Electronic Medical Record (EMR) for those with lipid labs and values that satisfy criteria for extreme values. Identified participants will be recruited to provide health information via survey, permission to extract clinical information from the EMR, and blood collection for future analyses. Measurements will span direct measurement of circulating species, genetic analyses, and analysis of circulating cells. The blood specimens will be stored for future studies and collaborations and thus, will constitute a blood-based repository. All study procedures are experimental but do not involve an actual intervention. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04156997
Study type Observational [Patient Registry]
Source University of Texas Southwestern Medical Center
Contact Shailesh Jaiswal
Phone 214-645-2049
Email Shailesh.Jaiswal@UTSouthwestern.edu
Status Recruiting
Phase
Start date May 10, 2019
Completion date May 2029

See also
  Status Clinical Trial Phase
Active, not recruiting NCT05565742 - A Study of LY3819469 in Participants With Elevated Lipoprotein(a) [Lp(a)] Phase 2
Completed NCT05563246 - A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events Phase 2
Recruiting NCT05496790 - Role of LipoprotEin(a) in CardiovascuLar Diseases and Premature Acute Coronary Syndromes - (RELACS) Study
Not yet recruiting NCT05081440 - A Multi-center, Prospective, Observational Study to Describe the siTuation of Blood Lipid mAnagement Among the Population With hypeRtension and/or Type 2 diabeTes in Community Health Center