Clinical Trials Logo
  1. Home
  2. Lipodystrophy
  3. NCT00715546
  4. Details
NCT00715546 Clinical Trial

Autologous Adipose-Derived Stem Cell Transplantation in Patients With Lipodystrophy

Lipodystrophy Clinical Trial

— AADSCTPL  

Official title:
Phase 1 Study of Autologous-Derived Stem Cell Transplantation in Patients With Lipodystrophy

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00715546
Other study ID # ISCMPA 1642/07
Secondary ID
Status Active, not recruiting
Phase Phase 1
First received July 11, 2008
Last updated June 21, 2011
Start date October 2007
Est. completion date November 2011

Study information
Verified date March 2009
Source Irmandade Santa Casa de Misericórdia de Porto Alegre
Contact n/a
Is FDA regulated No
Health authority Brazil: Ethics Committee
Study type Interventional

Clinical Trial Summary

The aim of this study is to determine the safety of the autologous transplantation of adipose-derived stem cells in the treatment of lipodystrophies.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 5
Est. completion date November 2011
Est. primary completion date August 2011
Accepts healthy volunteers No
Gender Both
Age group 20 Years and older
Eligibility Inclusion Criteria:

- lipodystrophies with necessity of fat grafting

- accept to participate of the study

Exclusion Criteria:

- HIV infection

- Metastatic malignancy

- Body mass index < 20 kg/m²

- Other severe systemic disease

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Procedure:
• autologous transplantation of liposuction material enriched with adipose-derived stem cells
Lipoinjection enriched with adipose-derived stem-cells.

Locations
Country Name City State
Brazil Irmandade Santa Casa de Misericórdia Porto Alegre Rio Grande do Sul

Sponsors (1)
Lead Sponsor Collaborator
Irmandade Santa Casa de Misericórdia de Porto Alegre

Country where clinical trial is conducted

Brazil, 

Outcome
Type Measure Description Time frame Safety issue
Primary Clinical evaluation of the transplanted area. one year Yes
Secondary Presence of neovascularization, adipose transplantation reabsorption, tissue viability one year Yes
See also
  Status Clinical Trial Phase
Recruiting NCT05419037 - Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy
Recruiting NCT03059121 - The Cleveland Cardiometabolic Cohort
Completed NCT00656175 - Raltegravir Therapy for Women With HIV and Fat Accumulation Phase 2
Completed NCT00006185 - Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome Phase 1
Completed NCT00202241 - The Effects of Anabolic Steroids and Protease Inhibitors on People Living With HIV/AIDS N/A
Recruiting NCT02262832 - Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy Phase 3
Completed NCT01679197 - Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy Phase 2
Completed NCT02647853 - Phase 1 Study to Assess the Safety and Tolerability of TAT4 Gel in Healthy Volunteers Phase 1
Completed NCT00069004 - A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth N/A
Completed NCT00025883 - Leptin to Treat Lipodystrophy Phase 2
Completed NCT00001142 - Metabolism and Body Shape of Healthy Children and Children With Chronic Infections N/A
Active, not recruiting NCT02262806 - Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy Phase 2
Completed NCT02258685 - Factors Mediating Gut Microbiota Dysbiosis and Metabolic Disease in HIV Patients.
Completed NCT00192621 - Seronegatives and Metabolic Abnormalities Protocol 2 (SAMA002): Study to Compare the Effect of Kaletra and Combivir® in HIV-Negative Healthy Subjects Phase 4
Completed NCT00006190 - A Study to Determine How and Why HIV-Infected Subjects on Anti-viral Treatment Develop Lipodystrophy Phase 4
Recruiting NCT05930106 - Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management N/A
Completed NCT00004329 - Study of Alpha-2 Adrenergic Receptor Dysfunction in Regional Lipoatrophy N/A
Recruiting NCT04656054 - Hemoglobin Level, Coagulopathy Profile and Electrolyte Balance
Completed NCT00082628 - Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients Phase 3
Withdrawn NCT01788462 - Egrifta Replacement and Sleep Disordered Breathing N/A