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Effects of a Large Increase in Dietary Fats and Cholesterol on HDL Composition and Function in Healthy Subjects

Lipids Clinical Trial

Official title:
Effects of a Large Increase in Dietary Fats and Cholesterol on HDL Composition and Function in Healthy Subjects

Clinical Trial Summary

In this study the investigators aimed at measuring the effect of a two-week high-fat/high-cholesterol (HFHC) normocaloric diet on HDL particles biochemical composition and HDL function compared to a two-week low-fat/low-cholesterol (LFLC) normocaloric diet.

Clinical Trial Description

HDL particles can change their composition and function in response to a variety of pathological conditions and environmental stimuli. It has been previously shown that a western diet is able to drastically modify biochemical composition, anti-inflammatory and anti-oxidant properties of HDL in animals. In humans little is known on the role of diet on HDL function and composition. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02549144
Study type Interventional
Source Azienda Ospedaliero, Universitaria Pisana
Contact
Status Completed
Phase N/A
Start date January 1, 2015
Completion date December 1, 2015
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