Lipid Metabolism Disorders Clinical Trial
Official title:
Evaluation of Omega 3 Supplementation on Neurological Recovery , Lipid Profile and Antioxidant Enzymes and Hormones After Chronic Spinal Cord Injury.
The objective of this study is to evaluate the effect of omega 3 fatty acid on neurological
recovery, lipid profile and Antioxidant system in patients with spinal cord injury. One
hundred spinal cord injured patients who come to clinic of spinal injury repair research
center selected. Then the patients will receive two supplements capsules of omega 3 (600 mg)
in the intervention group and placebo in the control group. Primary outcome measures are
professionals evaluation of neurological function by using :
- ASIA scale for sensory and motor function
- FIM scale for Functional potential
- FAM
- SF_36 for quality of life
Lipid profile and Antioxidant profile evaluation by using:
- FBS
- 2hpp
- Insulin
- LDL
- Total cHOL
- TG
- HDL
- Leptin Adiponectin -Calcium-
- 25OHD
- PTH,LH, FSH, Prolactin,Testosterone in males Bone markers by serum levels of
:Osteocalcin-Osteoprotegrin_Bone Specified ALP- CTX - RANKL
- BMD
All no neurological evaluation will be done by experiment researcher under considering of a neurologist.All Sub clinical evaluation will be done by specific, sensitive and valid laboratory methods. Intervention time will be 14 months.Comparison of these variables will be done before and after intervention. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04896619 -
Cholesterol Effects of Kori-tofu Proteins
|
N/A | |
| Completed |
NCT01737164 -
Effect of Age on Glucose and Lipid Metabolism
|
N/A | |
| Completed |
NCT05629403 -
Exclusive Breastfeeding Improves Puerperal Glucose Metabolism in Pregnant Women With Gestational Diabetes Mellitus and Links to Lipids Composition
|
||
| Withdrawn |
NCT03047538 -
Fixed Combination for Lipid and Blood Pressure Control
|
Phase 4 | |
| Withdrawn |
NCT02270164 -
The Impact of Artichoke Leaf Extract on Blood Cholesterol: Primary Study
|
N/A | |
| Completed |
NCT01968720 -
Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia
|
Phase 2 | |
| Completed |
NCT01435382 -
A Pharmacokinetic and Pharmacodynamic Study of PF-04950615 (RN316) in Subjects With Hypercholesterolemia
|
Phase 1 | |
| Completed |
NCT00707746 -
Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects
|
Phase 2 | |
| Active, not recruiting |
NCT01803776 -
The Physical Activity and Nutrition in Children (PANIC) Study
|
N/A | |
| Active, not recruiting |
NCT05618756 -
CBD, Nutrient Metabolism and Energy Intake
|
N/A | |
| Completed |
NCT05558488 -
The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune Response
|
N/A | |
| Recruiting |
NCT04948008 -
Evaluate the Efficacy and Safety of IBI306 in Subjects With Homozygous Familial Hypercholesterolemia
|
Phase 2/Phase 3 | |
| Completed |
NCT03898505 -
Clinical Investigation on the Safety of Avocado Pulp Lipids
|
Early Phase 1 | |
| Terminated |
NCT01963650 -
Natural History Study of Children With Metachromatic Leukodystrophy
|
||
| Not yet recruiting |
NCT06060886 -
Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis
|
Phase 4 | |
| Completed |
NCT03976479 -
Body Composition, Nutritional and Cardiovascular Status and Lifestyle Factors of Adults Who Are on Plant-Based Diet
|
||
| Completed |
NCT02243969 -
Alpha-linolenic Acid and Blood Pressure
|
N/A | |
| Completed |
NCT01874132 -
Study of the Long-term Effects of Exercise on Heath Indicators in Older People
|
N/A | |
| Completed |
NCT00477594 -
Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia
|
Phase 2 | |
| Completed |
NCT05564676 -
Flaxseed Oil and Pomegranate Extract on Inflammation, Lipid Profile and Nutritional Status of Hemodialysis Patients
|
N/A |