Effect of Plasma Ceramides on Peripheral Vascular Function

Status Recruiting

Clinical Trial Summary

The goal of this clinical trial is to determine the effect of elevated plasma ceramides on peripheral vascular function. Subjects will consume a high fat meal consisting of long chain fatty acids (to increase plasma ceramides) or medium chain fatty acids (control). Subjects' vascular function will be assessed with laser Doppler flowmetry to measure their artery function and with the CytoCam device to assess their peripheral microvascular endothelial function.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05107869
Study type	Interventional
Source	Medical College of Wisconsin
Contact	Julie K. Freed, MD, PhD
Phone	414-955-7487
Email	jfreed@mcw.edu
Status	Recruiting
Phase	N/A
Start date	May 1, 2023
Completion date	December 31, 2027

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02122198` - Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women	N/A
Completed	`NCT04156711` - Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery	N/A
Recruiting	`NCT06133634` - Fisetin to Improve Vascular Function in Older Adults	Phase 1/Phase 2
Completed	`NCT05872139` - Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging	N/A
Recruiting	`NCT04558450` - Covid-19 Effects on Arterial Stiffness and Vascular Aging (CARTESIAN)	N/A
Terminated	`NCT03325933` - Resistance Training and Cardiometabolic Health	N/A
Not yet recruiting	`NCT05939934` - Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal	N/A
Completed	`NCT02652975` - Anticancer Treatment of Breast Cancer Related to Cardiotoxicity and Dysfunctional Endothelium	N/A
Recruiting	`NCT02334839` - The Association Between Severity of Hypertensive Disorder During Pregnancy and Endothelial Dysfunction	N/A
Recruiting	`NCT02020044` - Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)	N/A
Completed	`NCT01775865` - Targeting Inflammation to Treat Cardiovascular Aging	Phase 2
Completed	`NCT01691404` - Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLAVO)	N/A
Terminated	`NCT01412216` - The Effects of Sedentarism on Vascular Function, Inflammation, and Insulin Resistance	Phase 2
Completed	`NCT01319344` - Effect of Eplerenone on Endothelial Function in Metabolic Syndrome	Phase 3
Completed	`NCT00848302` - Endothelial Function in Human Arteries	Early Phase 1
Completed	`NCT00987974` - Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury	Phase 4
Completed	`NCT00990730` - Atherosclerosis in Rheumatoid Arthritis	N/A
Completed	`NCT00532844` - A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction	Phase 2
Completed	`NCT00376246` - Effect of Ezetimibe on Flow-mediated Brachial Artery Reactivity in Healthy Subjects	Phase 4
Completed	`NCT00775099` - Combustion Derived Air Pollution and Vascular Function	N/A