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Lipid Depletion clinical trials

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NCT ID: NCT03459209 Completed - Human Milk Clinical Trials

Effect of Tube Feeding on LCPUFAs Delivery

Start date: April 1, 2016
Phase:
Study type: Observational

Long-chain polyunsaturated fatty acids (LCPUFAs) docosahexaenoic (DHA) arachidonic acid (AA) are major building blocks for the lipid bilayer of neuronal and retinal membranes and play a crucial role in brain and visual development. Humans lack enzymes synthetizing DHA and AA precursors and thus rely upon dietary sources to achieve adequate intakes. Human milk (HM) feeding, either own mother's milk (OMM) or donor milk (DM), is the first nutritional choice for preterm infants and provides appropriate LCPUFAs amounts to support neurological and visual development of this fragile population. Due to their immaturity, preterm infants are often unable to coordinate sucking and swallowing, thus requiring tube feeding (TF) for prolonged time periods. During TF, fatty acids tend to separate from aqueous milk components and to adhere to the infusion set, thus reducing the delivery of HM lipid contents. To dare, however, a targeted evaluation of TF-related LCPUFAs losses has not been performed. This study aims to quantitatively assess, by means of gas chromatography coupled to mass spectrometry, the effect of bolus and different continuous feeding methods routinely adopted for preterm infants' enteral nutrition on the delivery of DHA and AA contained in human milk samples.

NCT ID: NCT02001402 Enrolling by invitation - Menopausal Syndrome Clinical Trials

Chinese Health Investigation of Nurse Aging

Start date: August 2008
Phase: N/A
Study type: Observational

A follow-up intervention for the climacteric symptoms of nurses in Peking