Lipedema Clinical Trial
Official title:
Comparison of Complete Decongestive Therapy (CDT) With Intermittent Pneumatic Compression (IPK) for Treatment of Lipedema
Verified date | January 2020 |
Source | Hitit University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Lipedema is a chronic, progressive and hereditary adipose tissue disorder characterized by an abnormal increase of subcutaneous adipose tissue, especially in the lower extremities. In contrast to obesity, lipoedema may not improve with weight loss and does not include the risk of metabolic syndrome such as diabetes, hypertension and dyslipidemia. However, if not treated for lipedema, medical complications such as hypermobility, joint problems, walking difficulties, and psychological complications such as anxiety and depression may develop.The aim of this study was to compare the effects of combined decongestive treatment and intermittent pneumatic compression treatment combined with aerobic exercise on pain, quality of life and fatigue in patients with lipedema.
Status | Completed |
Enrollment | 33 |
Est. completion date | December 22, 2019 |
Est. primary completion date | November 22, 2019 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Subject diagnosed with lipedema according to the criteria of revised Wold. - Subject did not participate in any exercise program within the last three months. - No pregnancy / breastfeeding Exclusion Criteria: - History of acute infection, cancer, inflammatory rheumatic / connective tissue diseases - History of cardiovascular or musculoskeletal problems that may prevent them from participating in the exercise program |
Country | Name | City | State |
---|---|---|---|
Turkey | Tugba Atan | Corum |
Lead Sponsor | Collaborator |
---|---|
Hitit University |
Turkey,
Canning C, Bartholomew JR. Lipedema. Vasc Med. 2018 Feb;23(1):88-90. doi: 10.1177/1358863X17739698. Epub 2017 Nov 16. Review. — View Citation
Reich-Schupke S, Schmeller W, Brauer WJ, Cornely ME, Faerber G, Ludwig M, Lulay G, Miller A, Rapprich S, Richter DF, Schacht V, Schrader K, Stücker M, Ure C. S1 guidelines: Lipedema. J Dtsch Dermatol Ges. 2017 Jul;15(7):758-767. doi: 10.1111/ddg.13036. — View Citation
WOLD LE, HINES EA Jr, ALLEN EV. Lipedema of the legs; a syndrome characterized by fat legs and edema. Ann Intern Med. 1951 May;34(5):1243-50. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Extremity volumetric measurement | Pythagorean theorem in the excel program. Pythagorean theorem will automatically calculate volumetric calculation. |
6 weeks | |
Secondary | Waist circumference | Waist circumference | 6 weeks | |
Secondary | Waist-to-hip ratio | Waist-to-hip ratio | 6 weeks | |
Secondary | 6-minute walk test | 6-Minute Walk Test is a submaximal exercise test usually corresponding to 80% of a subject's maximum heart rate and is used to assess functional capacity and treatment response. | 6 weeks | |
Secondary | Visual analog scale for pain | Pain intensity was measured with visual analogue scale for pain (0-10 mm; 0 means no pain, 10 means severe pain) which is used to measure musculoskeletal pain with very good reliability and validity. | 6 weeks | |
Secondary | Short Form Health Survey 36 (SF-36) physical performance subscore SF-36 contains 36 items which are used to evaluate the quality of life of patients with chronic pain. | Short Form Health Survey 36 (SF-36) physical performance subscore SF-36 contains 36 items which are used to evaluate the quality of life of patients with chronic pain. | 6 weeks | |
Secondary | Fatigue Severity Scale | Fatigue Severity Scale assesses the severity of fatigue during the last week in a 9-item questionnaire (1= strongly disagree, 7= strongly agree). Total score ranges from 9 to 63, with higher scores representing greater fatigue. | 6 weeks | |
Secondary | Beck Depression Inventory | This is a 21-item self-report questionnaire evaluating the presence and severity of depressive symptoms in the vegetative, emotional, cognitive and motivational domains. Scores of each item ranges from 0 to 3, higher scores mean higher risk of depression. | 6 weeks |
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