Corneal Epithelial Allograft From Living-related Donor for LSCD

Status Completed

Clinical Trial Summary

The purpose of the study is to explore whether femtosecond laser-assisted corneal epithelial allograft from living-related donor is more effective than limbal conjunctival allograft from living-related donor for ocular surface reconstruction in patients with limbal stem cell deficiency (LSCD).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Limbal Stem Cell Deficiency

Clinical Trial Details

NCT number	NCT03217435
Study type	Interventional
Source	Sun Yat-sen University
Contact
Status	Completed
Phase	N/A
Start date	July 27, 2017
Completion date	November 13, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02568527` - Biodegradable Synthetic Scaffold as a Substitute for hAM in Limbal Epithelial Cells Transplant in LSCD Patients	N/A
Completed	`NCT00736307` - Autologous Transplantation of Cultivated Limbal Stem Cells on Amniotic Membrane in Limbal Stem Cell Deficiency (LSD) Patients	Phase 1/Phase 2
Not yet recruiting	`NCT06412718` - Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies
Available	`NCT02149732` - Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation	Phase 1/Phase 2
Recruiting	`NCT06452316` - Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency	Phase 1
Terminated	`NCT02579993` - ABCB5 as a Prognostic Marker in Survival of Cultivated Limbal Stem Cell Transplantation	N/A
Recruiting	`NCT03943797` - Cultivated Autologous Oral Mucosal Epithelial Transplantation	Phase 1
Active, not recruiting	`NCT03549299` - Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD	Phase 1/Phase 2
Recruiting	`NCT03217487` - Corneal Epithelial Autograft for LSCD	N/A
Active, not recruiting	`NCT00845117` - Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency	Phase 1/Phase 2
Enrolling by invitation	`NCT03015779` - Transplantation of Autologous Oral Mucosal Epithelial Stem Cell Sheet for Treating Limbal Stem Cell Deficiency Disease	Phase 1/Phase 2
Active, not recruiting	`NCT02739113` - Cultivated Autologous Oral Mucosal Epithelial Transplantation for the Treatment of Ocular Surface Diseases	Phase 1/Phase 2
Not yet recruiting	`NCT06265298` - Implementation of a Protocol for the Transdifferentiation of Buccal Mucosal Epithelium Into Corneal Epithelium	N/A
Recruiting	`NCT01756365` - Autologous Cultured Corneal Epithelium (CECA) for the Treatment of Limbal Stem Cell Deficiency	N/A
Completed	`NCT02592330` - Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft	Phase 1/Phase 2
Recruiting	`NCT02318485` - Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter Trial	Phase 2
Withdrawn	`NCT01489501` - Multicenter Study of CAOMECS Transplantation to Patients With Total Limbal Stem Cell Deficiency	Phase 3