PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Healthy Volunteers.

Light; Therapy, Complications Clinical Trial

Official title: PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Normal Volunteers

Status Completed

Clinical Trial Summary

We are evaluating the effect of methylene blue and visible light activation on the microbiome of the skin.

Clinical Trial Description

Antiseptics are routinely utilized to prevent infections of vascular catheters. We are evaluating the addition of methylene blue and light activation on skin to determine whether this inexpensive and non-toxic treatment can decrease skin pathogens and prevent blood stream infections of long-term vascular catheters. This is a pilot study of normal volunteers to determine the effect on the microbiome of the addition of methylene blue and light activation on antiseptic-treated skin. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Light; Therapy, Complications

• NCT number: NCT01981460
• Study type: Interventional
• Source: Massachusetts General Hospital
• Status: Completed
• Phase: N/A
• Start date: May 2013
• Completion date: July 2013