Eye Movement Behaviour and Pupil Size in Natural Outdoor and Indoor Scenes

Light Sensitivity Clinical Trial

Official title:

Characterization of Eye Movement Behaviour and Pupil Size Through Eye-tracking in Natural Outdoor and Indoor Scenes

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05971238
• Other study ID #: MPI-TSCN-2023-NATURALEYE
• Secondary ID: 2023-231-S-KH
• Status: Recruiting
• Phase: N/A
• Start date: July 1, 2023
• Est. completion date: July 31, 2024

Study information

• Verified date: July 2023
• Source: Technical University of Munich
• Contact: Alexander Hahn
• Phone: +49(0)70716011670
• Email: alexander.hahn[@]tuebingen.mpg.de
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this study, the researchers will be using eye tracking and detailed lighting measurements to understand how different types of indoor and outdoor lighting affect the eye movements and pupil sizes of our participants. Participants will be paired up and undergo six eye tracking sessions, split across two appointments. Each appointment will involve viewing either indoor or outdoor scenes, and before each session, participants will spend time adapting to the lighting conditions. Overall, each participant will spend 24 minutes being tracked, and the entire study will take about 2-3 hours to complete. The investigators expect differences in eye movements and pupil size between indoor and outdoor scenes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 24
• Est. completion date: July 31, 2024
• Est. primary completion date: August 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• No previous eye-surgeries or ocular impairments like anisometropia, amblyopia, strabism, cataract, watery eyes or hanging eye lids

• Normal or corrected-to-normal visual acuity (+3dpt. to -5dpt.)

• Normal colour vision

• Normal binocular vision

Exclusion Criteria:

• Any use of medications or drugs that influence photosensitivity or the ability to concentrate

• Excessive alcohol and/or drug use

• Presence of psychiatric disorders

• Poor sleep quality

• Diagnosed with epilepsy

Related Conditions & MeSH terms

• Light Sensitivity
• Photophobia

Intervention

Other:
• Indoor vs. outdoor scenes
Light conditions in indoor (artificial light) and outdoor (daylight) settings

Locations

Country	Name	City	State
Germany	Max Planck Institute for Biological Cybernetics	Tübingen

Sponsors (2)

Lead Sponsor	Collaborator
Technical University of Munich	Max-Planck Institute for Biological Cybernetics

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Saccade frequency - Indoor scene 1	Number per second [n/s]	Baseline
Primary	Saccade frequency - Indoor scene 2	Number per second [n/s]	Baseline
Primary	Saccade frequency - Indoor scene 3	Number per second [n/s]	Baseline
Primary	Saccade frequency - Outdoor scene 1	Number per second [n/s]	Baseline
Primary	Saccade frequency - Outdoor scene 2	Number per second [n/s]	Baseline
Primary	Saccade frequency - Outdoor scene 3	Number per second [n/s]	Baseline
Primary	Saccade amplitude - Indoor scene 1	Mean angular distance traveled [°]	Baseline
Primary	Saccade amplitude - Indoor scene 2	Mean angular distance traveled [°]	Baseline
Primary	Saccade amplitude - Indoor scene 3	Mean angular distance traveled [°]	Baseline
Primary	Saccade amplitude - Outdoor scene 1	Mean angular distance traveled [°]	Baseline
Primary	Saccade amplitude - Outdoor scene 2	Mean angular distance traveled [°]	Baseline
Primary	Saccade amplitude - Outdoor scene 3	Mean angular distance traveled [°]	Baseline
Primary	Saccade velocity - Indoor scene 1	Mean peak velocity [°/s]	Baseline
Primary	Saccade velocity - Indoor scene 2	Mean peak velocity [°/s]	Baseline
Primary	Saccade velocity - Indoor scene 3	Mean peak velocity [°/s]	Baseline
Primary	Saccade velocity - Outdoor scene 1	Mean peak velocity [°/s]	Baseline
Primary	Saccade velocity - Outdoor scene 2	Mean peak velocity [°/s]	Baseline
Primary	Saccade velocity - Outdoor scene 3	Mean peak velocity [°/s]	Baseline
Primary	Fixation duration - Indoor scene 1	Mean fixation duration [s]	Baseline
Primary	Fixation duration - Indoor scene 2	Mean fixation duration [s]	Baseline
Primary	Fixation duration - Indoor scene 3	Mean fixation duration [s]	Baseline
Primary	Fixation duration - Outdoor scene 1	Mean fixation duration [s]	Baseline
Primary	Fixation duration - Outdoor scene 2	Mean fixation duration [s]	Baseline
Primary	Fixation duration - Outdoor scene 3	Mean fixation duration [s]	Baseline
Primary	Fixation frequency - Indoor scene 1	Number per minute [n/min]	Baseline
Primary	Fixation frequency - Indoor scene 2	Number per minute [n/min]	Baseline
Primary	Fixation frequency - Indoor scene 3	Number per minute [n/min]	Baseline
Primary	Fixation frequency - Outdoor scene 1	Number per minute [n/min]	Baseline
Primary	Fixation frequency - Outdoor scene 2	Number per minute [n/min]	Baseline
Primary	Fixation frequency - Outdoor scene 3	Number per minute [n/min]	Baseline
Primary	Pupil size - Indoor scene 1	Mean pupil size [mm]	Baseline
Primary	Pupil size - Indoor scene 2	Mean pupil size [mm]	Baseline
Primary	Pupil size - Indoor scene 3	Mean pupil size [mm]	Baseline
Primary	Pupil size - Outdoor scene 1	Mean pupil size [mm]	Baseline
Primary	Pupil size - Outdoor scene 2	Mean pupil size [mm]	Baseline
Primary	Pupil size - Outdoor scene 3	Mean pupil size [mm]	Baseline
Primary	Melanopic irradiance - Indoor scene 1	Irradiance [W/(sqm*nm)]	Baseline
Primary	Melanopic irradiance - Indoor scene 2	Irradiance [W/(sqm*nm)]	Baseline
Primary	Melanopic irradiance - Indoor scene 3	Irradiance [W/(sqm*nm)]	Baseline
Primary	Melanopic irradiance - Outdoor scene 1	Irradiance [W/(sqm*nm)]	Baseline
Primary	Melanopic irradiance - Outdoor scene 2	Irradiance [W/(sqm*nm)]	Baseline
Primary	Melanopic irradiance - Outdoor scene 3	Irradiance [W/(sqm*nm)]	Baseline
Primary	Photopic illuminance - Indoor scene 1	Illuminance [lux]	Baseline
Primary	Photopic illuminance - Indoor scene 2	Illuminance [lux]	Baseline
Primary	Photopic illuminance - Indoor scene 3	Illuminance [lux]	Baseline
Primary	Photopic illuminance - Outdoor scene 1	Illuminance [lux]	Baseline
Primary	Photopic illuminance - Outdoor scene 2	Illuminance [lux]	Baseline
Primary	Photopic illuminance - Outdoor scene 3	Illuminance [lux]	Baseline
Secondary	Subjective scene ratings - Indoor scene 1	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.): 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Secondary	Subjective scene ratings - Indoor scene 2	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.): 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Secondary	Subjective scene ratings - Indoor scene 3	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.): 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Secondary	Subjective scene ratings - Outdoor scene 1	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.): 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Secondary	Subjective scene ratings - Outdoor scene 2	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.): 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Secondary	Subjective scene ratings - Outdoor scene 3	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.): 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Secondary	Geographical scene location - Indoor scene 1	Longitude and latitude [°]	Baseline
Secondary	Geographical scene location - Indoor scene 2	Longitude and latitude [°]	Baseline
Secondary	Geographical scene location - Indoor scene 3	Longitude and latitude [°]	Baseline
Secondary	Geographical scene location - Outdoor scene 1	Longitude and latitude [°]	Baseline
Secondary	Geographical scene location - Outdoor scene 2	Longitude and latitude [°]	Baseline
Secondary	Geographical scene location - Outdoor scene 3	Longitude and latitude [°]	Baseline
Secondary	Ambient temperature - Indoor scene 1	Temperature [°C]	Baseline
Secondary	Ambient temperature - Indoor scene 2	Temperature [°C]	Baseline
Secondary	Ambient temperature - Indoor scene 3	Temperature [°C]	Baseline
Secondary	Ambient temperature - Outdoor scene 1	Temperature [°C]	Baseline
Secondary	Ambient temperature - Outdoor scene 2	Temperature [°C]	Baseline
Secondary	Ambient temperature - Outdoor scene 3	Temperature [°C]	Baseline