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Lidocaine clinical trials

View clinical trials related to Lidocaine.

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NCT ID: NCT06379490 Recruiting - Lidocaine Clinical Trials

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Start date: April 23, 2024
Phase: Phase 3
Study type: Interventional

To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties of the LIC block with short- and long-acting local anesthetics in different concentrations but at the same volume. In addition to motor and sensory blockade during repositioning, feasibility will also be assessed by other patient-related and block-related factors, as well as by factors related to the repositioning and plastering procedure.

NCT ID: NCT06355817 Completed - Surgery Clinical Trials

Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration

Start date: September 21, 2023
Phase: N/A
Study type: Interventional

To compare the efficacy of topical tapping vs vibration in lowering pain scores for periocular anesthesia injections.

NCT ID: NCT06344637 Active, not recruiting - Pain, Procedural Clinical Trials

Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration

Start date: December 14, 2023
Phase: N/A
Study type: Interventional

This randomized control trial aim to evaluate the effectiveness of local lidocaine spray application to the cervix on the reducing of pain score during the manual vacuum aspiration

NCT ID: NCT06226532 Not yet recruiting - Intubation Clinical Trials

Effect of Lidocaine Sprayed for Attenuating Hemodynamic Response During Laryngoscopy and Intubation

Start date: January 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to to evaluate the efficacy of lidocaine sprayed at the laryngeal inlet combined with the endotracheal tube cuff compare with intravenous lidocaine on the hemodynamic response to laryngoscopy and intubation in patients undergoing elective neurological procedures during general anesthesia with total intravenous technique. The main question it aims to answer is: - Does topical lidocaine sprayed at the laryngeal inlet combined with the endotracheal tube cuff have more effect on stabilizing hemodynamic responses to laryngoscopy and intubation than intravenous lidocaine, in neurosurgical patients who undergo general anesthesia with total intravenous technique? Participants will be recruited and randomized to receive either lidocaine spray (Group SL) or intravenous lidocaine (group IL) to blunt hemodynamic response to laryngoscopy and intubation.

NCT ID: NCT06184282 Completed - Lidocaine Clinical Trials

Topical Mebo Versus Lidocane in Healing Time of Traumatic Oral Ulcer

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

This study aims to assess topical MEBO application on pain relief and wound healing.

NCT ID: NCT06135688 Completed - Lidocaine Clinical Trials

Effects of Lidocaine Bolus and Infusion on Bispectral Index Values and Spectrum During Anesthesia Maintenance

Start date: November 18, 2023
Phase:
Study type: Observational

Lidocaine has been shown to increase the hypnotic effects of Propofol, however no trials shows the effects on Bispectral Index Values (BIS) and spectral analysis during total intravenous anesthesia maintenance delivered with target controlled infusion (TCI) with stable Concnetration at the effector site of Propofol (CeP)

NCT ID: NCT06107543 Recruiting - Lidocaine Clinical Trials

Lidocaine in the Prevention of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation

Start date: December 1, 2023
Phase:
Study type: Observational

Direct laryngoscopy and endotracheal intubation procedure stimulate the sympathetic nervous system, causing catecholamine release into the circulation and consequently hemodynamic changes.There are many studies showing that lidocaine is used intravenously to suppress the sympathetic response to laryngoscopy and endotracheal intubation. Nebulized lidocaine is often used to provide upper airway local anesthesia in fiberoptic guided awake intubation. In this study, the researchers aimed to compare the results of using intravenous lidocaine and nebulized lidocaine to suppress the hemodynamic response caused by laryngoscopy and endotracheal intubation retrospectively. Researchers' hypothesis; Nebulized lidocaine administration is more effective than intravenous lidocaine administration in suppressing the hemodynamic response due to laryngoscopy and endotracheal intubation in patients under general anesthesia.

NCT ID: NCT06088875 Recruiting - Dexmedetomidine Clinical Trials

Nebulization Versus Spray-as-You-Go Airway Topical Anesthesia Using Dexmedetomidine and Lidocaine Mixture During Awake Flexible Fiberoptic Intubation in Temporomandibular Ankylosis

Start date: October 18, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of airway topical anesthesia with nebulization to the spray-as-you-go technique using dexmedetomidine and lidocaine mixture to achieve upper airway anesthesia in TMJ ankylosis patients.

NCT ID: NCT05937282 Recruiting - Dexmedetomidine Clinical Trials

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

Start date: July 1, 2023
Phase: Phase 4
Study type: Interventional

This study will be carried out to compare the efficacy of dexmedetomidine, propofol or lidocaine infusions in attenuation of hemodynamic responses to pneumoperitoneum during adult laparoscopic cholecystectomy using electrical cardiometry.

NCT ID: NCT05935449 Completed - Lidocaine Clinical Trials

The Clinical Trial of Difference Between Formaderm Lidocaine and Formaderm Dermal Filler Injection

Start date: August 4, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Lidocaine to the correction of nasolabial folds wrinkle and reduction of pain immediately after treatment. The main questions it aims to answer are: 1. The pain score assessed using Visual Analog Pain Scale(VAS) and Thermometer Pain Scale(TPS). 2. The facial wrinkle assessed using Wrinkle Severity Rating Scales(WSRS). 3. The treatment improvement assessed using Global Aesthetic Improvement Scale (GAIS). 4. Safety Indicators of which incidences on the day of the injection or after the injection. Participants will be self-controlled and randomized for same period, - received both trial product and control product at the same time. - re-visited on Day 14 and Day 30 after injection. The researchers will compare whether Formaderm Lidocaine is superior to Formaderm Dermal Filler Injection (without lidocaine) in terms of pain relief experienced by subjects during injection.