Clinical Trials Logo
  1. Home
  2. Lichen Planus
  3. NCT05787925

Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level in Patients With Erosive Oral Lichen Planus

Lichen Planus Clinical Trial

Official title:
The Efficacy of Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level In Patients With Erosive Oral Lichen Planus (A Randomized Controlled Clinical Trial)

Clinical Trial Summary

Oral lichen planus (OLP) is a chronic inflammatory disease affecting the skin, mucous membranes,s and rarely scalp and nails. It is a T-cell-mediated autoimmune disease. Traditional treatment for OLP is topical steroids commonly used to treat mild to moderately symptomatic lesions. Recent treatment modalities for oral lichen planus include micronutrients such as antioxidants including vitamin E that modify the immune system function. The aim of this study is to evaluate the efficacy of adjunctive oral systemic vitamin E therapy on salivary nitric oxide levels in patients with erosive oral lichen planus.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05787925
Study type Interventional
Source Alexandria University
Contact
Status Completed
Phase N/A
Start date October 20, 2022
Completion date March 5, 2023
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT06021405 - Koebner's Phenomenon in Psoriasis and Lichen Planus N/A
Recruiting NCT03340155 - Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases N/A
Completed NCT03630198 - Pain Outcomes Following Intralesional Corticosteroid Injections Phase 4
Completed NCT04952961 - Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention Study N/A
Recruiting NCT04697563 - Laser Therapy in Women With Lichenoid Disorders N/A
Recruiting NCT06451744 - Cellular and Molecular Biomarkers in Patients With Lichen Planus N/A
Completed NCT03265093 - Use of Injectable Platelet Rich Fibrin in Lichen Planus N/A
Completed NCT03858634 - A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases Phase 2
Completed NCT02761122 - Implication of Human Papillomavirus (HPV) in Lichen Physiopathology in Human (HPVLichen) N/A
Active, not recruiting NCT00691106 - A Multi-center Study to Evaluate the Safety of Etanercept in the Treatment of Lichen Planus Phase 2
Terminated NCT05761158 - Study of the Characteristics of Pruritus in Patients With Frontal Fibrosing Alopecia or Lichen Planus Pilaris
Recruiting NCT02261662 - Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV Infection N/A
Not yet recruiting NCT04892381 - Assessment of PD-1 and PD-L1Tissue Expression Levels in Lichen Planus Patients: A Case-Control Study
Completed NCT05396261 - a Flexible Wound Dressing for the Management of Genital Skin Conditions N/A
Recruiting NCT02532166 - Incidence of Esophageal Lichen Planus in Patients With Known Oral Lichen Planus N/A
Recruiting NCT06327620 - Treatment Of Oral Lichen Planus N/A
Completed NCT03796806 - Methods Validation Assessment for Study of Inflammatory Skin Disease
Completed NCT02850601 - Dexamethasone Solution for the Treatment of Oral Lichen Planus Phase 2
Not yet recruiting NCT01041625 - Pilot Study of Apremilast (CC-10004) in the Treatment of Moderate to Severe Lichen Planus Phase 2
Completed NCT00824889 - Exploratory Study of Natural Killer Cells in Human Skin N/A