Leukemia Clinical Trial
Official title:
Pharmacogenetics of Gemtuzumab Ozogamicin (GO) Therapy in Acute Myeloid Leukemia
Verified date | May 2016 |
Source | Children's Oncology Group |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Observational |
RATIONALE: DNA analysis of blood and tissue samples may help doctors predict how well
patients will respond to treatment. It may also help doctors learn more about how gemtuzumab
ozogamicin works in the body.
PURPOSE: This research study is looking at gemtuzumab ozogamicin in DNA samples from
patients with acute myeloid leukemia treated on COG-AAML0531.
Status | Completed |
Enrollment | 1000 |
Est. completion date | |
Est. primary completion date | May 2016 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A to 29 Years |
Eligibility |
DISEASE CHARACTERISTICS: - Diagnosed with acute myeloid leukemia - DNA samples from patients treated on COG-AAML0531 PATIENT CHARACTERISTICS: - Not specified PRIOR CONCURRENT THERAPY: - See Disease Characteristics |
Observational Model: Case-Only, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Children's Oncology Group | National Cancer Institute (NCI) |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Genetic changes in CD33 impact outcome of gemtuzumab ozogamicin-based therapy | No |
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