Leukemia Clinical Trial
Official title:
Sirolimus and Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor Hematopoietic Cell Transplantation
A continuation study of sirolimus and mycophenolate mofetil (MMF) for graft-vs-host disease (GvHD) prophylaxis for patients undergoing matched related allogeneic hematopoietic stem cell transplantation (HSCT) for acute and chronic leukemia, myelodysplastic syndrome (MDS), high risk non-Hodgkin lymphoma (NHL), or Hodgkin lymphoma (HL)
To explore the novel combination of sirolimus and mycophenolate mofetil (MMF) as
graft-vs-host disease (GvHD) prevention in human leukocyte antigen (HLA)-matched related
donor peripheral blood stem cell (PBSC) or marrow transplantation (BMT), collectively
hematopoietic stem cell transplantation (HSCT). This study will report the toxicities
associated with this drug combination.
For all treatments and procedures, Study Day is based on the day of HSCT as Day 0.
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