Leukemia Clinical Trial
Official title:
CC-1088 Therapy for Chronic Lymphocytic Leukemia: A Phase I/II Trial
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die.
PURPOSE: Phase I/II trial to study the effectiveness of CC-1088 in treating patients who
have chronic lymphocytic leukemia that has not responded to previous therapy.
OBJECTIVES: I. Determine the toxicity of CC-1088 in patients with refractory, progressive,
B-cell chronic lymphocytic leukemia. II. Determine the response rate to this treatment in
these patients.
OUTLINE: Patients receive oral CC-1088 three times a day for 28 days. Treatment continues in
the absence of disease progression or unacceptable toxicity.
PROJECTED ACCRUAL: A total of 11-20 patients will be accrued for this study.
;
Primary Purpose: Treatment
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