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Clinical Trial Summary

This study will evaluate the efficacy and safety of LBH589B in adult patients with chronic myeloid leukemia who are in accelerated phase or blast phase (blast crisis) with resistant disease following treatment with at least two BCR-ABL tyrosine kinase inhibitors


Clinical Trial Description

study was designed to assess the hematologic response associated with treatment of oral panobinostat. Hematologic response is defined as the overall of complete hematologic response (CHR), and of no evidence of leukemia (NEL) and of the return to chronic phase (RTC). Hematologic responses were to be confirmed after 4 weeks, and all criteria listed below for each type of response were to be concomitantly met to result into a response. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00449761
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 2
Start date February 23, 2007
Completion date August 26, 2008

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