Leukemia, Myeloid, Acute Clinical Trial
Official title:
Impact of Washed Transfusions in Adult Patients With Acute Myeloid or Lymphoid Leukemia
Verified date | April 2017 |
Source | University of Rochester |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature.
Status | Completed |
Enrollment | 100 |
Est. completion date | November 2016 |
Est. primary completion date | November 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 50 Years |
Eligibility |
Inclusion Criteria: - previously untreated patients with a diagnosis of acute leukemia between the ages of 0 and 50 (AML) and 18 and 50 (ALL) Exclusion Criteria: - all other patients |
Country | Name | City | State |
---|---|---|---|
United States | Strong Memorial Hospital (University of Rochester Medical Center) | Rochester | New York |
Lead Sponsor | Collaborator |
---|---|
University of Rochester |
United States,
Blumberg N, Heal JM, Rowe JM. A randomized trial of washed red blood cell and platelet transfusions in adult acute leukemia [ISRCTN76536440]. BMC Blood Disord. 2004 Dec 10;4(1):6. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Survial Rate at 30 Days | The percentage of patients who were alive at 30 days after transfusion. | 30 days | |
Primary | Survial Rate at 60 Days | The percentage of patients who were alive at 60 days after transfusion. | 60 days | |
Primary | Survial Rate at 100 Days | The percentage of patients who were alive at 100 days after transfusion. | 100 days | |
Primary | Survial Rate at 5 Years | The percentage of patients who were alive at 5 years after transfusion. | 5 years |
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