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Leukemia, Lymphocytic, Acute clinical trials

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NCT ID: NCT00185523 Terminated - Leukemia Clinical Trials

Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)

Start date: May 2002
Phase: Phase 2
Study type: Observational

The purpose of the study is to evaluate the overall and disease free survival of recipients who have received G-CSF mobilized stem cells from HLA matched sibling donors.

NCT ID: NCT00176930 Terminated - Multiple Myeloma Clinical Trials

Stem Cell Transplant for Hematological Malignancy

Start date: October 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to develop a standard of care treatment using allogeneic stem cells for patients with cancers of the blood. The protocol was revised to reflect that this study is considered "treatment guidelines", rather than a research study.

NCT ID: NCT00176839 Terminated - AML Clinical Trials

Stem Cell Transplantation for Hematological Malignancies

Start date: June 7, 2000
Phase: Phase 2/Phase 3
Study type: Interventional

This protocol using busulfan, cyclophosphamide and melphalan has been designed as conditioning therapy for patients receiving stem cell transplantation for acute leukemia or myelodysplastic syndrome (MDS). The hypothesis is that this new regimen will be well tolerated and will cure the patient.

NCT ID: NCT00167180 Terminated - Multiple Myeloma Clinical Trials

Post Transplant Donor Lymphocyte Infusion

Start date: January 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the hypothesis that a pre-infusion preparative regimen of cyclophosphamide and fludarabine will improve the effectiveness of DLI in patients with blood cancers.

NCT ID: NCT00167167 Completed - AML Clinical Trials

Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia

Start date: December 1995
Phase: N/A
Study type: Interventional

In this study our hypothesis is that infusion of donor lymphocyte immune cells from the subject's bone marrow donor will activate the subject's immune system to attack their cancer.

NCT ID: NCT00067002 Completed - Clinical trials for Lymphoma, Non-Hodgkin

Randomized Double Cord Blood Transplant Study

Start date: April 2003
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to learn if combining cord blood units to make the cells "take" faster in recipients will help to improve the results of cord blood transplants.

NCT ID: NCT00038883 Terminated - Lymphoma, B-Cell Clinical Trials

Campath-1H and Allogeneic Blood Stem Cell Transplantation for Lymphoid Malignancies

Start date: April 9, 2001
Phase: N/A
Study type: Interventional

High dose chemotherapy followed by transplantation of allogeneic hematopoietic stem cell with the use of Campath-1h, a monoclonal antibody that have a synergistic effect to chemotherapy with minimal toxicity. In addition Campath-1H can improve engraftment of donor cells through its immunosuppressive properties.

NCT ID: NCT00005892 Completed - Clinical trials for Myelodysplastic Syndromes

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Start date: March 2000
Phase: N/A
Study type: Interventional

OBJECTIVES: I. Determine the effectiveness of moderate dose cyclophosphamide and radiotherapy in terms of improving survival and reducing the morbidity following allogeneic bone marrow transplantation in patients with myelodysplastic syndrome and acute leukemia related to Fanconi's anemia.