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Leukemia, Erythroblastic, Acute clinical trials

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NCT ID: NCT02527174 Withdrawn - Clinical trials for Leukemia, Myeloid, Acute

A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia

VIAC
Start date: November 2016
Phase: Phase 1
Study type: Interventional

This is a Phase I clinical trial to determine the maximum tolerated dose (MTD) of the polo-like kinase-1 inhibitor volasertib which can be safely combined with idarubicin plus cytarabine induction chemotherapy for previously untreated patients with acute myeloid leukemia. (AML).

NCT ID: NCT01835288 Withdrawn - Clinical trials for Recurrent Adult Acute Myeloid Leukemia

Arsenic Trioxide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Start date: May 2013
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well arsenic trioxide works in treating patients with relapsed or refractory acute myeloid leukemia. Drugs used in chemotherapy, such as arsenic trioxide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.

NCT ID: NCT00101140 Withdrawn - Clinical trials for Adult Acute Myeloid Leukemia

Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia in Remission

Start date: n/a
Phase: Phase 2
Study type: Interventional

RATIONALE: A peripheral stem cell transplant may be able to replace blood-forming cells that were destroyed by chemotherapy or radiation therapy. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving total-body irradiation together with fludarabine, thiotepa, and antithymocyte globulin before transplant may stop this from happening. PURPOSE: This phase II trial is studying how well a donor stem cell transplant works in treating patients with acute myeloid leukemia in remission.