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Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma

Leiomyosarcoma Clinical Trial

Official title:
Randomized, Controlled, Open-label, Phase IIb/III Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Patients With Metastatic Leiomyosarcoma

Clinical Trial Summary

The primary objective of this phase IIb/III study is to evaluate whether the combination of lurbinectedin plus doxorubicin given as first line treatment for metastatic leiomyosarcoma (LMS) prolongs the progression-free survival (PFS) by Independent Review Committee (IRC) when compared to doxorubicin administered as a single agent.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06088290
Study type Interventional
Source PharmaMar
Contact Gaston Federico Boggio, M.D.
Phone +34 91 823 4524
Email gfboggio@pharmamar.com
Status Recruiting
Phase Phase 2/Phase 3
Start date September 21, 2023
Completion date November 26, 2026
View Details
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