Leiomyoma Clinical Trial
Official title:
Phase 1 Study of Misoprostol in Reducing Intraoperative Bleeding in Myomectomy Operations
The aim of this research work is to assess the effect of using single preoperative dose of rectal misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications
This study is a randomized, double-blind, controlled study that will be conducted in Ain
Shams University Maternity Hospital.
A total of 50 women scheduled to undergo myomectomy for symptomatic uterine myoma will be
included in this study after taking their consent for this clinical trial after full
explanation of the trial.
The total of 50 included patients will be divided into two groups: Group A (Study group;):
will Include 25 patients undergoing myomectomy operation will receive two tablets of
misoprostol (400 mcg) rectally two hours before the operation.Group B (Control group): will
Include 25 patients undergoing myomectomy operation will not receive misoprostol before the
operation.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
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