Trial of Mifepristone for Fibroids

Status Completed

Clinical Trial Summary

The purpose of this trial is to determine if low-dose mifepristone benefits women with symptomatic fibroids.

Clinical Trial Description

This trial is designed to assess the efficacy and tolerability of mifepristone 5 mg given daily for 6 months to pre-menopausal women with symptomatic fibroids. The primary study outcome will be disease-specific quality of life. Secondary outcome measures include global quality of life, pain, bleeding, potential adverse effects, tumor size, and endometrial effects. The researchers will also examine a the effect of mifepristone on uterine blood flow. Randomization of study subjects will be stratified in order to ensure that equal numbers of women with moderate and severe symptoms will be enrolled in the placebo and control groups. ;

Study Design

Related Conditions & MeSH terms

Leiomyoma

Clinical Trial Details

NCT number	NCT00133705
Study type	Interventional
Source	University of Rochester
Contact
Status	Completed
Phase	Phase 3
Start date	July 2003
Completion date	June 2010

View Details

See also
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