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Leiomyoma clinical trials

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NCT ID: NCT05840042 Not yet recruiting - Uterine Fibroid Clinical Trials

Epidemiology and Risk Factors of Uterine Fibroids in China

Start date: June 19, 2023
Phase:
Study type: Observational

Uterine fibroids are the most common form of benign uterine tumors in the uterine muscle layer, which had a certain rate of malignancy, but it is rare. The prevalence of uterine fibroids estimates range from 4.5% to 68.6% depending on study population and diagnostic methodology. The prevalence of fibroids has been historically underestimated by epidemiologic studies which focused mainly on symptomatic women, leaving behind a large population of asymptomatic women and women who underreport their symptoms. What investigators don't know was which women who have fibroids will develop clinical symptoms and which women who have an operation of myomectomy will relapse. The purpose of this study is to investigate the prevalence, incidence and risk factors for the development of uterine fibroids in Chinese women.

NCT ID: NCT05695690 Not yet recruiting - Uterine Fibroid Clinical Trials

Role of US in Uterine Fibroids in Comparison With MRI Using FIGO Classification

Start date: May 2023
Phase:
Study type: Observational

Evaluation of diagnostic accuracy of ultrasound in uterine fibroid characterization compared with MRI using FIGO classification

NCT ID: NCT05569200 Not yet recruiting - Clinical trials for Benign Uterine Tumor

The Clinical Trial About Treatment of Benign Uterus Myoma by Haifu Focused Ultrasound Tumor Therapeutic System

Start date: December 2022
Phase: N/A
Study type: Interventional

Uterine benign tumor including myoma is the most common female benign pelvic tumor. Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) has been considered to be a minimal invasive treatment. The device used in this trial will be Haifu Focused Ultrasound tumor therapeutic System. In this trial, the investigators will observe the possibility of complication and tumor response of treatment.

NCT ID: NCT05151393 Not yet recruiting - Clinical trials for Vitamin D Deficiency

Correlation Between Serum Vitamin D3 and Incidence of Uterine Leiomyoma

Start date: December 1, 2021
Phase:
Study type: Observational

The aim of the current study is to evaluate the association between low serum vitamin D level and incidence of uterine leiomyoma in Egyptian women as the research hypothesis that low serum vitamin D is considered a risk factor for uterine leiomyoma

NCT ID: NCT04960293 Not yet recruiting - Clinical trials for Symptomatic Uterine Fibroids

Spherical Gelfoam Versus Tri-acryl Microsphere for Uterine Artery Embolization for Symptomatic Fibroids

Start date: July 2021
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare pain after uterine artery embolization using spherical gelfoam or tris-acryl gelatin microsphere in patients with symptomatic fibroids

NCT ID: NCT04364581 Not yet recruiting - Myoma;Uterus Clinical Trials

Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary Lesions

Start date: May 1, 2020
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate the effectiveness of short course of letrozole for endometrial preparation before hysteroscopic surgery for intracavitary lesions.

NCT ID: NCT04282863 Not yet recruiting - Clinical trials for Surgical Procedure, Unspecified

Comparison Between Robotic (RM) and Laparoscopic Myomectomy (LM)

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

This is a single-blinded RCT evaluating the effect of robotic-assisted (RM) or conventional laparoscopic surgery (LM) in the management of uterine leiomyomas.

NCT ID: NCT04250766 Not yet recruiting - Fibroid Uterus Clinical Trials

Diagnostic Performances of Preoperative Echo-guided Uterine Biopsy in the Management of Suspect Uterine Sarcoma Tumors (BIOPSAR)

BIOPSAR
Start date: June 2020
Phase: N/A
Study type: Interventional

This is a prospective multi-center interventional study that will be performed in an effort to assess the diagnostic accuracy performance of preoperative vaginal ultrasound-guided biopsy (VUGB) to detect the exact histology of uterine tumors and thereafter triage cases being eligible for morcellation during laparoscopic resection. Ten tertiary French centers will participate in the present study.

NCT ID: NCT04192812 Not yet recruiting - Uterine Fibroid Clinical Trials

PREOPERATIVE GONADOTROPINE-RELEASING HORMONE AGONIST THERAPY BEFORE SURGERY FOR UTERİN FIBROIDS

Start date: December 30, 2020
Phase: N/A
Study type: Interventional

Uterin fibroids are the most common operation indication for hysterectomy. Dyring laparoscopic hysterectomy the amount of bleeding is a great difficulty.There are a lot of clinical researchs to reduce the haemorrhage during open hysterectomy but not laparoscopic procedure. In ALKU ERH clinic, researchers decided to smaller the size of fibroid by using GnRH analogues before total laparoscopic hysterectomy to reduce the haemorrhage amount.

NCT ID: NCT04192643 Not yet recruiting - Uterine Fibroid Clinical Trials

INTERVENTION WITH TRANEXAMIC ACID TO REDUCE HAEMORRHAGE DURING LAPAROSCOPIC MYOMECTOMY

Start date: December 30, 2020
Phase: N/A
Study type: Interventional

This research is planned as a randomised double-blind controlled trial. interventions to reduce haemorrhage during laparoscopic myomectomy for fiboids is important. İntraoperative Tranexamic acid usage can reduce haemorrhage and related symptoms when given during laparoscopic myomectomy. There is no randomised controlled trials in literature about tranexamic acid usage in laparoscopic gynecological operations.