Clinical Trials Logo
  1. Home
  2. Left Ventricular Dysfunction
  3. NCT05650008
  4. Details
NCT05650008 Clinical Trial

Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

Left Ventricular Dysfunction Clinical Trial

Official title:
Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05650008
Other study ID # 21263
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 1, 2023
Est. completion date October 10, 2023

Study information
Verified date November 2023
Source Milton S. Hershey Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The objective of this study is to assess the effects of intrathecal local anesthetics on left ventricular global longitudinal strain (LVGLS) using transthoracic echocardiography (TTE).

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date October 10, 2023
Est. primary completion date October 10, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Adult patients undergoing elective knee and hip replacements under spinal anesthesia Exclusion Criteria: - Patients who do not wish to consent - Patients with contraindications to TTE - Patients with reduced left ventricular systolic function as defined by LV ejection fraction < 50% on pre-operative echocardiography - Patients with body mass index greater than 40 - Non-English-speaking subjects - Cognitively impaired adults

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Intrathecal local anesthesia
Administration of local anesthetic into intrathecal space to achieve surgical anesthesia

Locations
Country Name City State
United States Milton S. Hershey Medical Center Hershey Pennsylvania

Sponsors (1)
Lead Sponsor Collaborator
Milton S. Hershey Medical Center

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Left Ventricular Global Longitudinal Strain 5 minutes
Secondary Left Ventricular Ejection Fraction 5 minutes
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT05529654 - IMpella-Protected cArdiaC Surgery Trial (IMPACT) N/A
Recruiting NCT04671966 - Sex Differences in Myocardial Steatosis Induced Left Ventricular Dysfunction Phase 4
Not yet recruiting NCT05188222 - Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery Phase 4
Recruiting NCT04950218 - The Psoriasis Echo Study
Completed NCT01076920 - Mesenchymal Stem Cells and Myocardial Ischemia Phase 1/Phase 2
Completed NCT01128790 - Pilot Study of Remote Ischemic Preconditioning in Heart Failure N/A
Completed NCT04942353 - Effects of Home-based Exercise Rehabilitation on Healthcare Utilization in HeartMate 3 Patients N/A
Recruiting NCT05769036 - Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients N/A
Completed NCT03232736 - InterventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With LVAD's
Recruiting NCT04694092 - Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial Fibrillation N/A
Completed NCT01609738 - Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum Phase 1/Phase 2
Completed NCT02013037 - The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation Phase 3
Completed NCT00551681 - Effects of Left Ventricular Pacing Optimilization on Cardiac Perfusion, Contractile Force, and Clinical Performance in Patients With Ventricular Dysfunction and Heart Failure N/A
Not yet recruiting NCT04103008 - Left Ventricular Function After Primary Percutaneous Coronary Intervention: Role of Speckle Echocardiography
Completed NCT06197256 - Cardiac Dysfunction in Critically Ill Covid-19 Patients
Recruiting NCT05860504 - Acute Cardiac Dysfunction in Critical Illnes
Completed NCT03787810 - Left Ventricular Dysfunction in Critically Ill Patients
Completed NCT01093001 - Tricuspid Regurgitation Study Phase 4
Active, not recruiting NCT00461734 - PROTECT-PACE STUDY - The Protection of Left Ventricular Function During Right Ventricular Pacing N/A
Recruiting NCT04752293 - Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)