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Leeches clinical trials

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NCT ID: NCT05438901 Completed - Leeches Clinical Trials

Investigation of Oxidant-antioxidant Status in Patients Treated With Hirudotherapy

Start date: March 29, 2021
Phase: N/A
Study type: Interventional

Hirudotherapy (HT); It is a traditional treatment method applied using medicinal leeches such as Hirudo Medicinalis and Hirudo Verbana. Purpose of the study titled "Investigation of oxidant-antioxidant status in patients treated with hirudotherapy": To investigate the effect of HT on oxidative stress in healthy individuals.

NCT ID: NCT04676581 Completed - Clinical trials for Healthcare Associated Infection

Risk Benefit Ratio of Hirudotherapy: Retrospective Single-center Study of 37 Cases Over a Period of 9 Years

AMLEE
Start date: December 15, 2020
Phase:
Study type: Observational

Venous congestion in transplanted or re-implanted tissues remains a common and chal-lenging complication in plastic and reconstructive surgery. Local application of medicinal leeches is effective to reduce postoperative venous congestion of the flap and to restore normal blood flow. However, leech therapy is associated with a number of risks, including infections. Indeed, leeches maintain a symbiotic relationship with Aeromonas species in order to digest blood in their gut. Aeromonas spp. infections can occur 1 to 30 days post-application of leeches and are associated with a dramatic decrease in flap salvage rates (88 to 30%). For these reasons, prophylactic antibiotics and, external decontamination are widely recommended throughout the course of leech therapy. The aim of this study is to investigate the prevalence of side effects (anemia and infection) from patients treated with leeches in French Hospital.