Does Muscle Mass at Intensive Care Unit Admission Determine Mortality: The Memo Study — MEMO  

Lean Body Mass Clinical Trial

Official title: Does Muscle Mass at Intensive Care Unit Admission Determine Mortality: The Memo Study

Status Active, not recruiting

Clinical Trial Summary

This retrospective monocentric study aims to investigate whether a low muscle mass at ICU admission and its loss over the ICU stay predicts mortality, and in what proportion we can counteract it by nutritional support.

Clinical Trial Description

The study hypothesis is that a low muscle mass at ICU admission, measured at the level of L3 on CT scans performed for clinical routine, and its change over the ICU stay predict the prognosis of the patient, especially the 30-day mortality, that it may at least be partly counteracted by nutritional support and that it is related with higher ICU and hospital costs.

The objectives of this retrospective study are to determine:

1. the link between baseline body composition at ICU admission and outcomes, such as 30-day, ICU and hospital mortality and LOS, and infections. If this is confirmed, we aim to evaluate the added values of body composition to ICU severity scores to predict 30-day mortality

2. the link between baseline body composition vs. other locations to predict outcomes

3. the impact of body composition changes on the afore-mentioned outcomes. If this is confirmed, we aim to evaluate the added value of changes in body composition to changes in ICU severity scores to predict 30-day mortality

4. the impact of nutritional support on body composition changes ;

Related Conditions & MeSH terms

• Lean Body Mass

• NCT number: NCT05834894
• Study type: Observational
• Source: University Hospital, Geneva
• Status: Active, not recruiting
• Start date: January 1, 2010
• Completion date: January 31, 2024