Early Exposure to Lead and Adult Antisocial Outcomes

Lead Poisoning Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00285610
• Other study ID #: 11261-CP-003
• Status: Completed
• Phase: N/A
• First received: February 1, 2006
• Last updated: November 17, 2014
• Start date: November 2001
• Est. completion date: October 2006

Study information

• Verified date: November 2014
• Source: National Institute of Environmental Health Sciences (NIEHS)
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Observational

Clinical Trial Summary

Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 225
• Est. completion date: October 2006
• Est. primary completion date: October 2006
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria: (1) Part of original CLS birth cohort -

Exclusion Criteria: (1) Moved out of geographic area

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Lead Poisoning

Locations

Country	Name	City	State
United States	Children's Hospital Medical Center	Cincinnati	Ohio

Sponsors (1)

Lead Sponsor	Collaborator
National Institute of Environmental Health Sciences (NIEHS)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Lead Exposure and Antisocial Behavior		Prenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years)