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Exposure, Dose, Body Burden and Health Effects of Lead

Lead Poisoning Clinical Trial

Official title:
Exposure, Dose, Body Burden and Health Effects of Lead

Clinical Trial Summary

This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system. A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea. Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone. Subjects are tested three times each over three years. Several genetic factors are also being assessed for the role they play in the health effects of lead. These genes are known to differ among individuals. We are interested to know whether different forms of the same genes can modify the effect lead has on health.

Clinical Trial Description

n/a

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00013819
Study type Observational
Source National Institute of Environmental Health Sciences (NIEHS)
Contact
Status Completed
Phase N/A
Start date February 1997
Completion date February 2001
View Details
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