Early Exposure to Lead and Adolescent Development

Lead Poisoning Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00011674
• Other study ID #: 8158-CP-001
• Status: Completed
• Phase: N/A
• First received: February 26, 2001
• Last updated: March 22, 2006
• Start date: May 1997
• Est. completion date: May 2001

Study information

• Verified date: March 2006
• Source: National Institute of Environmental Health Sciences (NIEHS)
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Observational

Clinical Trial Summary

This prospective cohort study examines the role of prenatal and early postnatal lead exposure on the neuropsychological status and social adjustment of adolescents enrolled in the Cincinnati Lead Study. We are examining the relationship between moderate exposure to lead and neuropsychological deficits, difficulties in peer relationships, personality disturbances and juvenile delinquency. This birth cohort of approximately 300 subjects has been followed since 1980 with regularly scheduled assessments of blood lead concentrations, health history, social and hereditary factors, and neurobehavioral development.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 300
• Est. completion date: May 2001
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Subjects for the Cincinnati Lead Study were recruited prenatally if their mothers resided in areas within Cincinnati, Ohio where there has historically been a high incidence of lead poisoning. Infants were eligible for follow-up if they were greater than 1500 grams at birth and had no disqualifying medical conditions such as defined genetic syndromes or other serious complications that may adversely affect neurobehavioral development.

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

• Lead Poisoning

Locations

Country	Name	City	State
United States	Findlay Street Clinic	Cincinnati	Ohio

Sponsors (1)

Lead Sponsor	Collaborator
National Institute of Environmental Health Sciences (NIEHS)

Country where clinical trial is conducted

United States,