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NCT00000104 Clinical Trial

Does Lead Burden Alter Neuropsychological Development?

Lead Poisoning Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00000104
Other study ID # NCRR-M01RR00400-0587
Secondary ID M01RR000400
Status Completed
Phase N/A
First received November 3, 1999
Last updated June 23, 2005

Study information
Verified date December 2003
Source National Center for Research Resources (NCRR)
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Observational

Clinical Trial Summary

Inner city children are at an increased risk for lead overburden. This in turn affects cognitive functioning. However, the underlying neuropsychological effects of lead overburden and its age-specific effects have not been well delineated. This study is part of a larger study on the effects of lead overburden on the development of attention and memory. The larger study is using a multi-model approach to study the effects of lead overburden on these effects including the event-related potential (ERP), electrophysiologic measures of attention and memory are studied. Every eight months, for a total of three sessions the subjects will complete ERP measures of attention and memory which require them to watch various computer images while wearing scalp electrodes recording from 11 sites. It is this test that we are going to be doing on CRC. There will be 30 lead overburdened children recruited from the larger study for participation in the ERP studies on CRC. These 30 children will be matched with 30 children without lead overburden. This portion of the study is important in providing an index of physiological functioning to be used along with behaviorally based measures of attention and memory, and for providing information about the different measures.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria:

- Pregnant mothers of the Phillips neighborhood in Minneapolis, Minnesota. Subject recruitment will take place in local clinics which serve pregnant women and offspring

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Intervention

Procedure:
• ERP measures of attention and memory

Locations
Country Name City State
United States Department of Neurology 420 Delaware St. SE, Box 486 Mayo Minneapolis Minnesota

Sponsors (2)
Lead Sponsor Collaborator
National Center for Research Resources (NCRR) HRSA/Maternal and Child Health Bureau

Country where clinical trial is conducted

United States, 

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