Histological Change of The Dentinal-Pulp Complex and Root Resorption

Laser Clinical Trial

Official title:

Histological Changes of The Dentinal-Pulp Complex and Root Resorption in Maxillary Premolars With Intrusive Orthodontic Movements Under a Low Power Laser Effect

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01642693
• Other study ID #: 2006-007
• Status: Completed
• Phase: Phase 1/Phase 2
• First received: July 13, 2012
• Last updated: July 16, 2012
• Start date: June 2006
• Est. completion date: May 2009

Study information

• Verified date: July 2012
• Source: Universidad de Antioquia
• Contact: n/a
• Is FDA regulated: No
• Health authority: Colombia: National Institutes of Health
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.

Description:

Orthodontics movements can cause inflamatory changes in the pulp and external inflamatory root resorption, different methods have been suggested to control that changes as the use of the low power laser. The objective of this study is to evaluate the low power laser effect on the inflamatory pulpar change and inflamatory external root resorption in maxillary premolars with intrusive orthodontic movements of 4 ounces during 12 weeks. Total sample were 34 healthy teeth, 16 were used to evaluate the normal standar and 18 were divided in two groups, the experimental group with the low power laser effect had a dose of 18 joules after activations of the orthodontic intrusion and the control group had a simulated effect in the same orthodontic movement. Teeth were extacted after 12 weeks and histological changes were evaluated in the dentinal-pulp complex and the pesence of external inflamatory root resorption. Findins suggest that low power. Laser decreased the inflamatory changes of the dentinal - pulp complex and the severity of the external inflamatory root resorption.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: May 2009
• Est. primary completion date: May 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 13 Years to 23 Years

Eligibility

Inclusion Criteria:

• Patients with first premolar extraction indicated

• Patients with no sistemic diseases

• Healthy premolars with completed root and no trauma or restoration

Exclusion Criteria:

• Sistemics diseased

• Restoration, trauma in first premolars

• root uncompleted

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Histology
• Intrusion
• Laser
• Resorption
• Root Resorption

Intervention

Radiation:
• Low power laser in teeth after intrusive movement
Low power laser was aplied to premolar teeth under an intrusive movement to study histological changes and root resorption

Other:
• Simulated laser in teeth with intrusive movements
Simulated laser in teeth with intrusive movements for histological and root resorption changes

Locations

Country	Name	City	State
Colombia	Paula Villa M	Medellin	Antioquia

Sponsors (1)

Lead Sponsor	Collaborator
Universidad de Antioquia

Country where clinical trial is conducted

Colombia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Teeth with intrusive movement and low power laser	Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application	12 weeks	Yes
Secondary	Teeth with intrusive movements with no laser exposition	Histological changes and root resorption were assesed in Teeth with intrusive movement with no laser exposition	12 weeks	Yes

External Links

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