Clinical Trials Logo
  1. Home
  2. Laparotomy
  3. NCT03216759

Effects of Comprehensive Intestinal Protection Strategy on Postoperative Intestinal Complications — CIPS  

Laparotomy Clinical Trial

Official title:
Effects of Comprehensive Intestinal Protection Strategy on Postoperative Intestinal Complications in Patients Undergoing Laparotomy With General Anesthesia

Clinical Trial Summary

To investigate the morbidity of intestinal injury after open surgery and observe the effect of comprehensive intestinal protection strategy on postoperative intestinal complications in patients undergoing laparotomy with general anesthesia.

Clinical Trial Description

Perioperative intestinal injury is one of the common tissues and organs injury in surgical practice. However, there is a lack of effective means of prevention and treatment.The investigators previously found that ischemic preconditioning, IPC, and dexmedetomidine has protective effects on intestinal mucosal injury.

However, the combined effect of various factors has not been clinically validated. To explore the effect of comprehensive intestinal protection strategy on postoperative intestinal complications in patients undergoing laparotomy with general anesthesia,the investigators select the patients undergoing open surgery under general anesthesia as the study subjects and the concentration of intestinal fatty acid binding protein (I-FABP) as well as the incidence of digestive system complications in one week after operation are the main observation indexes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03216759
Study type Interventional
Source Nanfang Hospital of Southern Medical University
Contact Cai Li, M.D
Phone +86-18602017796
Email licaisysu@163.com
Status Not yet recruiting
Phase N/A
Start date August 2017
Completion date December 2018
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT03234543 - Remote Ischemic Conditioning in Abdominal Surgery N/A
Completed NCT03827291 - QL Block With Exparel in Colectomy Phase 4
Recruiting NCT01719796 - Effect of TAP Block on Ventilatory Function Following Abdominal Surgery Phase 2
Completed NCT02596269 - Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia Phase 2/Phase 3
Completed NCT00364741 - Supplemental Oxygen and Complications After Abdominal Surgery (The PROXI-trial) Phase 4
Completed NCT01723280 - Supplemental Oxygen - Effect on Occurrence of Subsequent Cancer After Abdominal Surgery (Follow-up of the PROXI Trial) N/A
Terminated NCT00514566 - PDS vs Polyamide for Midline Abdominal Closure N/A
Recruiting NCT06089551 - Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery Phase 4
Withdrawn NCT03966768 - DuraMesh Laparotomy Study N/A
Recruiting NCT04985695 - Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy N/A
Recruiting NCT03739944 - Different Surgical Approaches in Patients of Early-stage Cervical Cancer Phase 3
Terminated NCT01890408 - Continuous Preperitoneal Infusion of Ropivacaine After Open Liver Resection: Effect on Post-operative Recovery and Morbidity. Phase 2
Recruiting NCT00544583 - Continuous Versus Interrupted Abdominal Wall Closure After Emergency Midline Laparotomy Phase 2/Phase 3
Recruiting NCT04256798 - Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery Phase 3
Recruiting NCT03738969 - Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer
Completed NCT03989570 - Transversus Abdominis Plane Block Versus Erector Spinae Plane Block N/A
Not yet recruiting NCT04266535 - TCI vs Manually Controlled Infusion of Propofol
Completed NCT04065607 - Indications and Outcome of Laparostomy
Completed NCT01040013 - Gut Oxygenation and Laparoscopy Phase 2
Completed NCT00637936 - Respiratory Effects of Perioperative Oxygen During General Anaesthesia Phase 4