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Laparoscopic Cholecystectomy clinical trials

View clinical trials related to Laparoscopic Cholecystectomy.

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NCT ID: NCT06428084 Completed - Clinical trials for Laparoscopic Cholecystectomy

Comparative Efficacy of Dexamethasone - Ondansetron Versus Dexamethasone - Haloperidol in Reducing PONV

Start date: November 1, 2023
Phase: Phase 2
Study type: Interventional

Nausea and vomiting following laparoscopic cholecystectomy remain common, with occurrence rates of 40-70% during the initial 24 hours post-operation. The underlying mechanisms of postoperative nausea and vomiting engage five distinct neurotransmitter receptors. Consequently, employing a combination of antiemetics from diverse classes that target various receptors for effective prevention is advised. Ondansetron's antiemetic properties derive from its ability to inhibit serotonin receptors, whereas Haloperidol targets dopamine receptors, and Dexamethasone reduces prostaglandin production.

NCT ID: NCT06390280 Completed - Clinical trials for Postoperative Nausea and Vomiting

The Role of High Intraoperative Fraction of Inspired Oxygen in Preventing Postoperative Nausea and Vomiting

Start date: July 10, 2022
Phase:
Study type: Observational [Patient Registry]

Postoperative nausea and vomiting is one of the most common complications after laparoscopic surgeries. The investigators aimed to evaluate the effects of intraoperative high fraction of inspired oxygen in preventing postoperative nausea and vomiting according to Apfel score in laparoscopic cholecystectomy patients.

NCT ID: NCT06154928 Completed - Clinical trials for Laparoscopic Cholecystectomy

Effects of Warm Water on GI System in Laparoscopic Cholecystectomy Patients

LCSS
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Objective: The study was carried out to determine the effect of drinking warm water on GIS functions in patients who underwent laparoscopic cholecystectomy surgery.

NCT ID: NCT05998317 Completed - Postoperative Pain Clinical Trials

Dexamethasone at Night vs at Induction on PONV After Laparoscopic Cholecystectomy

Start date: October 8, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

Since the peak effect of the dexamethasone is delayed to 12-16 hours after iv administration, we designed this study to investigate the effect of administering dexamethasone at-night before surgery versus at-induction (the standard timing) in prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. A pilot randomized controlled study (60 cases) will be started to explore the potential difference, ensure correct and rigorous data collection, and calculate the sample size for a larger pragmatic trial.

NCT ID: NCT05951374 Completed - Clinical trials for Laparoscopic Cholecystectomy

Madany Triangle; a New Era of Laparoscopic Cholecystectomy

Start date: December 1, 2019
Phase:
Study type: Observational

Laparoscopic cholecystectomy has an increased incidence of extrahepatic biliary injury or bleeding. The common hepatic duct is on the medial border of the Calot triangle and at risk of injury. So, The investigators describe a new safety triangle with a more critical view of safety that is far from dangerous. Retrospectively, from December 2019 until March 2023, the investigators will review the medical records for patients who underwent laparoscopic cholecystectomy. The patients underwent cholecystectomy using a new technique in approaches to critical safety with recorded video and available follow up data were included. The patients who had intraoperatively extensive gallbladder adhesion that interfere with the dissection in this area, improper visualization of the cystic duct, patients whose did not operate by this new technique and patients whose have not video record of laparoscopic cholecystectomy will excluded from the study.

NCT ID: NCT05871424 Completed - Clinical trials for Laparoscopic Cholecystectomy

Transdermal Buprenorphine Patch for Laparoscopic Cholecystectomy

Start date: June 11, 2023
Phase: N/A
Study type: Interventional

Preliminary studies of the transdermal buprenorphine patch target chronic pain patients, and the pain relief effect and safety have been proven. There are previous reports that the transdermal buprenorphine patch is effective in acute postoperative pain control. However, no clinical studies have yet been reported on its application during laparoscopic cholecystectomy. Therefore, we designed this study to see if the use of a transdermal buprenorphine patch resulted in a better pain profile.

NCT ID: NCT05755815 Completed - Clinical trials for Laparoscopic Cholecystectomy

Retrolaminar Block Versus Intraperitoneal Block for Laparoscopic Cholecystectomy

Start date: May 21, 2023
Phase: N/A
Study type: Interventional

Although laparoscopic cholecystectomy is a minimally invasive surgery, it causes moderate-severe pain. The aim of this study is to assess the quality of pain relief in patients who will undergo in laparoscopic cholecystectomy surgery receiving either retrolaminar block or peritoneal block by comparing and evaluating the differences between the two techniques. It is hypothesized that retrolaminar block will be comparable to peritoneal block as a promising effective alternative for analgesia for in laparoscopic cholecystectomy surgeries with fewer side effects.

NCT ID: NCT05536557 Completed - Clinical trials for Laparoscopic Cholecystectomy

Bilateral External Oblique İntercostal (EOI) Plane Block in Patients Undergoing Laparoscopic Cholecystectomy.

Start date: September 15, 2022
Phase: N/A
Study type: Interventional

This study will define the postoperative analgesic effect of ultrasound-guided bilateral External Oblique İntercostal (EOI) Plane Block and compare the control group in patients undergoing laparoscopic cholecystectomy. The aim of this study is to compare postoperative opioid consumption of EOI plane block versus control group. It is hypothesized that postoperative opioid use will be less in patients with EOI plane block than in patients who only receive routine multimodal analgesia.

NCT ID: NCT05419947 Completed - Clinical trials for Laparoscopic Cholecystectomy

Clinical Trial for the Optimization of Indocyanine Green Administration in NIRF-C During L.Cholecystectomy.

DOTIG
Start date: June 20, 2022
Phase: Phase 4
Study type: Interventional

Laparoscopic cholecystectomy is one of the most performed surgical procedures worldwide. One of its most serious complications is injury to the main bile duct, with an incidence of less than 1%. There are different surgical strategies that try to reduce this complication, with indocyanine green fluorescence cholangiography being one of the most recent to appear. This technique is becoming a great tool during laparoscopic cholecystectomy. Despite the great rise of the procedure, today there is a great disparity in the administration protocols of indocyanine green during the procedure. Goals. The main objective of the study is to analyze whether there are differences between different types of doses and administration intervals of indocyanine green to obtain quality fluorescent cholangiography during laparoscopic cholecystectomy. In addition, the factors that influence the results of the technique will be sought.

NCT ID: NCT05366907 Completed - Clinical trials for Laparoscopic Cholecystectomy

Open Cholecystectomy Among Patients Undergoing Laparoscopic Cholecystectomy.

Start date: June 1, 2020
Phase:
Study type: Observational

In the current era, laparoscopic cholecystectomy is the treatment of choice for symptomatic gallstone disease. The aim of this study is to find out the prevalence of open cholecystectomy among patients undergoing laparoscopic cholecystectomy in a tertiary care center.