Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT04329143 |
| Other study ID # |
cystic duct stump stone |
| Secondary ID |
|
| Status |
Completed |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
January 1, 2013 |
| Est. completion date |
January 1, 2020 |
Study information
| Verified date |
March 2020 |
| Source |
Zagazig University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
Introduction: cholecystectomy relieves pre-surgical symptoms of gallbladder disease. The
persistence of symptoms was recorded in 10 - 20% of cases. Residual gall bladder/cystic duct
stump stone is one of the most important cause.
Aim: to compare between open and laparoscopic completion cholecystectomy of gall bladder
remnant and cystic duct stump syndrome as regard short and long term outcome.
Methods: This prospective study was conducted on 20 cases with residual GB/cystic duct stump
stone. The diagnosis was guided by ultrasound and magnetic resonance
cholangio-pancreatography. All cases were managed by using completion cholecystectomy -
either open or laparoscopic. All preoperative, operative, and postoperative data were
collected...
Description:
The incidence of gall bladder and cystic duct stump stones has been reported to be 5% of
patients after urgent cholecystectomy, and it is rare after elective operations . The
incidence of incomplete gallbladder removal following laparoscopic cholecystectomy is 13.3% .
Partial cholecystectomy may be resorted to in many conditions such as difficult dissection in
Calot's triangle that can be hazardous to common bile duct and/or blood vessels. In such
cases, many surgeons leave a part of the gall bladder in the manner described by author after
removing all stones from the remaining cuff of the gallbladder To prevent the incidence of
gallbladder remnant/cystic duct stump calculi, the cystic duct should be fully skeletonized
till 1 cm from the common bile duct. Stones in the cystic duct should be milked back to the
gallbladder before clipping Routine use of intraoperative cholangiography is not a must but
when used it can be useful in detecting calculi in the cystic duct The diagnosis of cystic
duct stump syndrome is always into the dilemma of post cholecystectomy syndromes and leads to
delayed diagnosis. Cystic duct stump syndrome may be misdiagnosed with reflux esophagitis,
peptic ulceration, irritable bowel syndrome or chronic pancreatitis hepatitis, mesenteric
ischemia, diverticulitis, and organic or motor intestinal disorders.
The imaging approach to post cholecystectomy syndrome includes ultrasonography, computed
tomography (CT) scan, endoscopic retrograde cholangiopancreatography (ERCP), and magnetic
resonance cholangiopancreatography (MRCP).
The purpose of this study is to emphasis that laparoscopic completion cholecystectomy is the
best surgical option for cystic duct stump and gall bladder remnant syndrome as regard safety
to the patients...
There may be gender specific risk factor for developing post-cholecystectomy syndrome, in
present study; the incidence was 70% in females (14 cases) compared to 30% in males (6
cases). This higher incidence in females was also reported , whom stated that the male to
female ratio was 1:1.45.
The symptoms of gall bladder syndrome may be nil or they can present with acute symptoms
(biliary colic, acute cholecystitis or acute pancreatitis) or chronic symptoms (persistent
right upper quadrant discomfort or pain, food intolerance, nausea or jaundice). The
persistence of symptoms after cholecystectomy points to the possibility of a gallbladder
remnant, especially when coupled with radiation of pain to the shoulder, food intolerance,
nausea or jaundice . abdominal pain and persistent dyspepsia as the commonest presentation
were stated by other study , while , reported that patients was referred to their institution
without persistent symptoms after cholecystectomy .In the present study, most cases presented
with right hypochondrial pain (18 cases) and asymptomatic cases are 2 cases and discovered
accidently by ultrasonography for other unrelated symptoms.
