Languages Clinical Trial
Proceed to an analysis of sensitivity and specificity results of the fMRI language network obtained in two ways: by providing a conventional language test and independent component analysis. These two methods will be compared to the reference method what the cortical intraoperative mapping.
Patients with brain tumors including malignant gliomas located in eloquent areas have long
been considered inoperable because of median survival and predictable postoperative
sequelae. The improved prognosis with chemoradiotherapy and surgical resection as complete
as possible questioned this attitude. The goal is to operate those patients without
additional disabilities. The cortical electrostimulation intraoperative mapping in awake
surgery can meet the eloquent areas. Identifying with fMRI these same areas to better
specify in advance the way initially and shortened the time to awake exploratory surgery
which improves patient comfort. However anxiety induced by the review in a pre-operative
setting, a debutante aphasia often make problematic the realization of a formal language
test. The analysis in the low frequency of spontaneous oscillations of large neuronal
networks can help isolate network of language at rest without particular language test at
the group analysis. This methodology, however, needs to be validated at the individual level
before it can be applied to pathology.
Proceed to an analysis of sensitivity and specificity results of the fMRI language network
obtained in two ways: by providing a conventional language test and independent component
analysis. These two methods will be compared to the reference method what the cortical
intraoperative mapping.
;
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03148470 -
Impact of Theta Burst Stimulation Over the Left DLPFC on Language Switching
|
N/A |