Lactic Acidosis Clinical Trial
OBJECTIVES: I. Study the metabolism of pyruvate and related problems in patients with lactic
acidemia.
II. Define the nature of the metabolic defect.
PROTOCOL OUTLINE: Patients fast for 6 hours. Glucagon IM is administered after the 6 hour
fast. Glucose level is measured at 0, 15, 30, 45, 60, and 90 minutes.
In children of sufficient size, alanine and lactic acid should also be measured at each or
most of these time points.
Fasting continues for at least 18 hours. Glucagon IM is administered again at end of fast.
Glucose level is measured at time 0, 15, 30, 45, 60, and 90 minutes.
;
N/A
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT00638040 -
The Gene Expression Studies of the Role of Tumor Microenvironments in Tumor Progression
|
N/A | |
Completed |
NCT00004493 -
Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia
|
Phase 2 | |
Completed |
NCT00004490 -
Phase III Randomized Study of Sodium Dichloroacetate in Children With Congenital Lactic Acidosis
|
Phase 3 | |
Withdrawn |
NCT03122678 -
Thiamine Supplementation in Patients With Septic Shock
|
Phase 1 | |
Recruiting |
NCT03126890 -
Investigation of the Correlation Between Plasma Concentration of Linezolid Antibiotic and Treatment Response and Adverse Reactions
|
||
Completed |
NCT01873859 -
Safety of Continuing Metformin in Diabetic Patients With Normal Kidney Function Receiving Contrast Media
|
N/A | |
Terminated |
NCT01354652 -
Lactic Acidosis During Entecavir(ETV)Treatment
|
Phase 4 | |
Terminated |
NCT02974257 -
Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest
|
Phase 2 | |
Active, not recruiting |
NCT05984186 -
Wingate-type Exercise Test to Evaluate the Effect of High Velocity Therapy on Recovery Sensation and Blood Lactate Decline
|
||
Completed |
NCT01139463 -
Study of Blood Lactate Levels in Patients Treated With Antipsychotics
|
N/A | |
Completed |
NCT01901419 -
Nitroglycerin Infusion During Cardiac Surgery
|
N/A | |
Completed |
NCT00202228 -
Lactate Metabolism Study in HIV Infected Persons
|
Phase 4 | |
Completed |
NCT04975906 -
The Threshold of Serum Anion Gap as a Screening Tool for Organic Acidosis
|
||
Completed |
NCT00942123 -
Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic Acidosis
|
N/A | |
Withdrawn |
NCT03723993 -
Remote Ischemic Preconditioning During Cardiopulmonary Bypass
|
N/A | |
Withdrawn |
NCT01973504 -
Phase 2c Dose Comparison Study of MP4OX in Trauma
|
Phase 2 | |
Completed |
NCT00015015 -
Dichloroacetate Kinetics, Metabolism and Toxicology
|
N/A | |
Completed |
NCT03466528 -
Alcohol: Thiamine and or Magnesium 1
|
Phase 2/Phase 3 |