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Lactation clinical trials

View clinical trials related to Lactation.

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NCT ID: NCT02719548 Completed - Lactation Clinical Trials

Impact of Breast Shield Designs on Dynamics of Breast Pumping

BSD
Start date: February 2016
Phase: N/A
Study type: Interventional

A prospective, randomized, 2-phase/crossover, single center premarket feasibility study. In phase I the comfort will be assessed, the occurence and types of adverse events will be recorded and the assessment how and if the different breast shield designs interact with the lacting breast during pumping. Phase II takes place at home; assessment of adverse events will be recorded and the assessment how the subjects perceives the comfort of the soft edge breast shield during mid term use at home.

NCT ID: NCT02690675 Completed - Clinical trials for Neurodevelopmental Disorders

Iron Supplement Effect on Child Development

Start date: May 2006
Phase: N/A
Study type: Interventional

Objective: To evaluate the effect of Iron supplement with two different amounts (one in the higher limit and another in the lower limit of the suggested amount) according to the presence of mutations in the HFE gene in the physical, immune and neurobehavioral development in the 6 to 12 moth toddlers. Methodology: Subjects: 340 toddlers coming from Paediatric Serves of Sant Joan Hospital. Methods: At 6 and 12 months it done clinical history, food registry, biochemist determinations: haemoglobin, iron, transferrin, ferritin, reactive C protein and immune response (IL4, IL10, IL6 IFN, IgA, IgM, IgG, IgE). Mutations in the HFE gene: C282Y, H63D, S65D and hepcidin gene. Mental, psychomotor and behavioual development (Bayley Scales of Infant Development 2on Edition: 1993). We evaluate the level of language and communication (MacArthur), regulation and sensory process (Infant Toddler Symptom Checklist), familiar and environment surroundings (Scale Health General Parental Stress Index).

NCT ID: NCT02662517 Completed - Lactation Clinical Trials

Growth Hormones and Cells in Human Milk Depending on Gestational Age

BMProfile
Start date: March 1, 2016
Phase:
Study type: Observational

Human breast milk contains growth factors including neurotrophins and cells with neuroprotective potential. Concerning growth factors milk of preterms differs significantly from term milk. The aim of this study is to give a profile of human milk concerning non-nutritive factors depending on gestational age and lactation phase.

NCT ID: NCT02621827 Completed - Pregnancy Clinical Trials

Vitamin D Half-life in Pregnancy and Lactation

Start date: November 2011
Phase: N/A
Study type: Interventional

This study measures the plasma half-life of 25-hydroxyvitamin D3 (25(OH)D3) in non-pregnant-non-lactating women, pregnant women at 30 wk gestational age and at 3 months post-partum in women who are exclusively breast-feeding.

NCT ID: NCT02542527 Completed - Lactation Clinical Trials

Evaluation of the Functionality of a Fluid Filled Single Breast Pump

C88
Start date: September 2015
Phase: N/A
Study type: Interventional

This study is an early (during the product development process) feasibility study. It shall evaluate the device design concept with respect to device functionality of a new fluid filled breast pump in a small number of subjects.

NCT ID: NCT02496429 Completed - Lactation Clinical Trials

Evaluation of the Reliability and Usability of the Reusable "BrownieForSymphony" Pump Set

ESP
Start date: July 2015
Phase: N/A
Study type: Interventional

The primary objectives of this study is to evaluate how professionals rate the reliability and usability of the reusable BrownieForSymphony pump set.and the current used Symphony pump set 4.2 Secondary Objectives The secondary objectives of this study are: - to evaluate the rate of usability problems with the BrownieForSymphony pump set - to evaluate the pragmatic quality (task/goal fulfilment) of the BrownieForSymphony pump set - to evaluate first impression of lactating woman regarding pumping with the BrownieForSymphony pump set

NCT ID: NCT02492139 Completed - Lactation Clinical Trials

Evaluation of the Reliability and Usability of the Reusable "BrownieForSymphony" Pump Set in Home Use

ESPII
Start date: July 2015
Phase: N/A
Study type: Interventional

The overall purpose of this study is to evaluate the reliability and usability of the reusable BrownieForSymphony pump set in home use. The primary objectives of this study is to asses and compare the System Usability Scale (SUS) score of the BrownieForSymphony pump set and the current used Symphony pump set. Secondary Objectives The secondary objectives of this study are: to evaluate the rate of usability problems with the BrownieForSymphony pump set - to evaluate the pragmatic quality (task/goal fulfilment) of the BrownieForSymphony pump set - to evaluate perceived comfort during pumping with the BrownieForSymphony pump set Prospective Cohort Study (quasi Cross over design)

NCT ID: NCT02384655 Recruiting - Lactation Clinical Trials

Effect of Fenugreek Use in Mothers of Preterm on Breast Milk Production and Macronutrient Content

Start date: March 11, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Feeding human milk to preterm infants does reduce the risk of serious and costly neonatal intensive care unit acquired morbidity such as NEC and the late onset sepsis. It is often difficult to obtain sufficient quantities of human milk from mothers of preterm infants most of whom are breast pump-dependent for weeks or months. Mothers will try to use galactogogues in an attempt to increase milk production. Fenugreek (Trigonella foenum-graecum) seeds is the most commonly used herbal galactogogue and is a member of the pea family. Our experience at the NICU is that around 30% of preterm mothers desperately looking for ways to increase their breast milk supply will eventually took fenugreek (Hilbe) as food supplement. Although widely recommended, there is limited evidence to support the effectiveness of fenugreek as a galactogogue. The aims of this study are to evaluate whether maternal consumption of fenugreek seeds has any effect on macronutrients composition of breast milk and whether fenugreek is transferred to the infant via mother milk. In addition any changes in mother and infant health status will be assessed.

NCT ID: NCT02378233 Terminated - Lactation Clinical Trials

Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant

Start date: October 2011
Phase: N/A
Study type: Interventional

The aim of the study is to measure urinary milk iodine concentration (MIC), iodine concentration (UIC), thyroid hormones (TSH, FT4) and thyroperoxidase antibodies (TPOab) in breast-feeding women, and UIC in their nursing infants to determine if the levels are adequate, and to see how they can be influenced by 150 ug daily iodine supplementation in breast-feeding women. The hypothesis is that there is a relative iodine deficiency in this sub-population - lactating women and nursing children-, and that this can be influenced by iodine supplementation. Adequate thyroid hormone and iodine levels are very important for small children, when the plasticity of the brain is greatest. This is as a prospective, double-blind, placebo-controlled study of 221 mothers and their infants. In parallel, 90 age-matched healthy non-pregnant women are recruited. Mothers are randomized to 150 µg/day iodide supplementation or placebo. Pregnant women are asked for participation on a visit in pregnancy week 37, at the mother health care (MVC) at Mölnlycke and Skövde. The study will run for approximately 3 months for each individual and begins by sampling A (UIC, TSH, FT4, TPOab) at week 37 of the pregnancy, when mothers also get randomized to 150 µg iodine or placebo. New sampling B (UIC, TSH, FT4, MIC ) is collected when the baby is 3 months old. Thereafter the study is completed. In parallel, 90 healthy non-pregnant, non-lactating women in the same age range are recruited and followed with UIC, TSH, FT4, TPOab for 6 months as a control group. In each case a simple questionnaire is filled and blood is also frozen for future analyses.

NCT ID: NCT02341027 Completed - Lactation Clinical Trials

Immediate Versus Interval Postpartum Use of the Levonorgestrel Contraceptive Implants: a Randomized Controlled Trial

Start date: January 2015
Phase: N/A
Study type: Interventional

This study will evaluate if immediate postpartum placement of a levonorgestrel (LNG) contraceptive implant within 5 days of delivery improves implant utilization at 6 months postpartum compared to implant placement at 6-8 weeks postpartum among women in Uganda.