Factors Influencing the Abortion Interval of Second-trimester Termination of Pregnancy Using Misoprostol

Labor Induction Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01927822
• Other study ID #: 102096-F
• Status: Completed
• Phase: N/A
• First received: August 18, 2013
• Last updated: July 4, 2015
• Start date: August 2013
• Est. completion date: August 2014

Study information

• Verified date: July 2015
• Source: Far Eastern Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This study aims to analyze the factors influencing the abortion interval of second-trimester termination of pregnancy using misoprostol.

Description:

Misoprostol is the primary drug of choice for medical termination. It is not only cheap, but also stable at room temperature and easily available worldwide. It is indicated for the treatment of gastritis, but is widely used off-label for a variety of indications in the practice of obstetrics and gynecology, including medication abortion, induction of labor, and the treatment of postpartum hemorrhage. The optimal dosage and route of administration have not been well defined and vary with physicians. The potency of misoprostol's effect varies with dosage, route of administration and dosing interval; both maternal and fetal factors may, to certain extent, affect the abortion interval. This study aims to analyze the factors influencing the abortion interval of second-trimester termination of pregnancy using misoprostol.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 101
• Est. completion date: August 2014
• Est. primary completion date: August 2014
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 13 Years to 50 Years

Eligibility

Inclusion Criteria:

1.All female patients who were admitted for medical termination of second-trimester pregnancy

Exclusion Criteria:

1. Patients who are allergy to Cytotec.

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Labor Induction

Locations

Country	Name	City	State
Taiwan	Far Eastern Memorial Hospital	New Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Successful termination rate by Cytotec.		1 week	Yes
Secondary	Factors affecting abortion interval by cytotec.	To identify the factors affecting termination interval Cox regression model.	1 week	No