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Oxytocin Versus, Sublingual Misoprostol in the Secondary Prevention of Postpartum Hemorrhage After Vaginal Delivery

Labor Complication Clinical Trial

Official title:
The Effect of Oxytocin Versus, Sublingual Misoprostol in the Secondary Prevention of Postpartum Hemorrhage After Vaginal Delivery: a Randomized Controlled Trial

Clinical Trial Summary

Researchers sought to see how oxytocin versus, sublingual misoprostol affected estimated and measured blood loss during vaginal delivery in women who had blood loss >300 ml .

Clinical Trial Description

The greatest cause of maternal mortality globally is postpartum hemorrhage (PPH), which is defined as a blood loss of 500 mL or more after birth. All women giving birth should be given a preventive uterotonic drug, according to the World Health Organization (WHO). Despite the use of a uterotonic drug as a preventative measure, PPH remains a frequent complication, accounting for one-quarter of all maternal fatalities worldwide. When prophylaxis fails and PPH develops, it is advised that uterotonic medicines be used as first-line therapy. However, it's unclear whether the uterotonic drug is better for treating PPH as first-line therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05077540
Study type Interventional
Source Aswan University Hospital
Contact hany f sallam, md
Phone +201112501460
Email hany.farouk@aswu.edu.eg
Status Not yet recruiting
Phase N/A
Start date November 1, 2021
Completion date December 31, 2023
View Details
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