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Clinical Trial Summary

The proposed study intends to investigate several aspects of the respiratory effects of intravenous sedation of patients undergoing spinal anesthesia for knee replacement surgery. The study will include assessment of PaCO2 during the intraoperative period. PaCO2 is expected to be elevated as a result of intravenous sedation and postural factors. Further, the study will investigate how application of Nasal Continuous Positive Airway Pressure (N-CPAP) may impact PaCO2.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care


Related Conditions & MeSH terms


NCT number NCT01622647
Study type Interventional
Source Mednax Center for Research, Education and Quality
Contact
Status Completed
Phase N/A
Start date July 2012
Completion date August 2013

See also
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Recruiting NCT06234631 - Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty Phase 2
Completed NCT01375231 - Anatomic Reconstruction of the Patellofemoral Joint Phase 4
Completed NCT01213602 - Bilateral Bispectral Index (BIS)-Monitoring in Trauma Surgery N/A